Spectrum of Leprosy Patients with Clinico-Histopathological Correlation: A Hospital Based Study

Singh, Arjun; Gaur, Rajesh; Ambey, Ravi

doi:10.3126/ajms.v4i4.7997

Cited by 7 publications

(11 citation statements)

References 7 publications

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“…In this study, age, sex group distribution are in accordance with the epidemiology of leprosy reported in literature. 1,[13][14][15][16] The age of the patients varied from 8 to 66 years, similar to the observation by Thakkar et al 17 Maximum number of patients belonged to the age group of 31-40 years followed by 21-30. Similar pattern is observed in others studies also.…”

Section: Discussionsupporting

confidence: 64%

Clinical profile and deformities in leprosy patients: a record based study

2020

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Background: Leprosy is a chronic disease caused by Mycobacterium leprae, infectious in some cases, and affecting the peripheral nervous system, skin and certain other tissues. Even though leprosy was declared eliminated as a public health problem in India on December 2005, new cases of leprosy continue to appear. Hence a study on clinical profile and deformities in all leprosy cases registered in the last 5 years was done to know the current status of leprosy in this area.Methods: This was a retrospective record-based study of leprosy cases done at Government Medical College, Manjeri, for a period of 5 years from October 2014 to September 2019.Results: 42 cases from the record were included in the study. Maximum cases belonged to the age group of 31 to 40 and males were more than females. 81% of the patients were multibacillary leprosy (MB) and 8 cases belonged to paucibacillary (PB) leprosy. Four child cases were registered as PB cases. Mostly encountered clinical diagnosis was borderline tuberculoid leprosy (23 out of 42) and two had type 1 reaction. Seven patients had deformity of which two had grade 2 deformity and rest had grade 1 deformity.Conclusions: One patient who presented with grade 2 deformity and type 1 reaction was from tribal area indicating low awareness about leprosy among them. More number of cases in the multibacillary group and presence of child cases and deformities reinforces the need for strict surveillance to eradicate leprosy.

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Section: Discussionsupporting

confidence: 64%

Clinical profile and deformities in leprosy patients: a record based study

2020

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“…Similar findings are noted by other studies. 5,6,10,11 Generally leprosy believed to be common in males. In the present study gender wise marginal male predominance was observed with male to female ratio of 1.33:1.…”

Section: Histopathological Pattern Of Diseasementioning

confidence: 99%

“…8 Histo-pathological examination is required when there is difficulty in diagnosing the cases clinically. 4,5,7 Thus histopathological examination is the gold standard for the accurate diagnosis of leprosy. It is also useful in classifying the cases accurately.…”

Section: Histopathological Pattern Of Diseasementioning

confidence: 99%

“…the historical trend of the disease; the impact of interventions; the efficacy of Histopathological examination is important for exact classification of leprosy, and confirmation of suspected cases with varied presentations and complications so as to provide appropriate management of patients. [4][5][6][7] Histopathological examination provides early & accurate diagnosis.…”

Section: Introductionmentioning

confidence: 99%

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A study of leprosy patients attended tertiary care hospital

Kadam

Ashtekar

Pawar

et al. 2016

Int J Community Med Public Health

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Background: Recorded leprosy case load has come down from to less than one case per 10,000 populations at national level in December 2005. Considerable changes in the epidemiological pattern of the disease have been observed due to the historical trend of the disease; the impact of interventions; the efficacy of chemotherapy and the role of improved health services. This study was planned to know the pattern of leprosy cases attending tertiary care hospital, their treatment & outcome. Methods: It is a retrospective study conducted from Bharati Vidyapeeth Deemed University Medical College & Hospital from 2007 till December 2015. Study-subjects include patients with leprosy and sample size includes all the patients of leprosy from January 2007 to December 2015. The study-tools: records, biopsy tissue blocks. Statistical analysis: percentages. Results: There were total 42 cases. Total 9.5% were children. Male to female ratio was 1.33:1. Two (4.8%) patients gave family history of leprosy, 23 (54.8%) were from rural area. Clinically 16.66% patients had single patch, 50% had nerve involvement. The most common type was borderline tuberculoid leprosy (35.7%). Out of these 42 cases 22 cases had completed the treatment, 14 on treatment. Six patients were defaulted. Conclusions: Early diagnosis & treatment of leprosy is happening as none of the cases had disability. History of contact in study subject was not common & presence of leprosy in paediatric age group indicates continued transmission. However there is a need of strong follow-up system for defaulters.

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“…Similar findings are noted by other studies. 11,12,13,14,15 Generally leprosy believed to be common in males. In the present study gender wise male predominance was observed with male to female ratio of 2.14:1.…”

Section: Discussionmentioning

confidence: 99%

Pattern and Complications of Leprosy among Patients attended Leprosy Clinic, Jesu Ashram, Siliguri, West Bengal: A 3 Years Record Based Study

Tirkey¹

2019

jmscr

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Introduction: Leprosy is a chronic infectious disease caused by Mycobacterium leprae and widely prevalent in India. Deformities are the common complications of leprosy. Plantar ulceration is the commonest serious disability in leprosy and they occur in about 10-20% of leprosy patients. Objectives: This study was planned to know the pattern and complications of leprosy and to ascertain the socio-demographic profile of Leprosy cases. Methods: A record based cross-sectional study was conducted for 3 months in 2019. All the registered cases of Leprosy patients at the Leprosy Clinic, Jesu Ashram, Siliguri, West Bengal, during last 3 years (2016 -2018 were included in the study, and their relevant records were reviewed using predesigned schedule. Collected data were analyzed using appropriate statistical measures. Results: There were total 884 cases. Male to female ratio was 2.14:1. Total 1.4% were children. 162 (19.2%) patients gave family history of leprosy, 531 (62.9%) were from rural area. The most common type was Multi-bacillary leprosy 659 (78.1%). Total 695 (82.3%) of the patients had Plantar ulcer deformity and 819 (97%) of the cases had absent nerve sensation. Conclusion: Majority of patients had plantar ulcer deformity. It indicates that the patients were not aware of it & not sought the consultation for the same at the earliest. Cases of Multi-bacillary (MB) leprosy are predominant. There is a need of strong follow-up system for defaulters in order to reduce the deformities.

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Spectrum of Leprosy Patients with Clinico-Histopathological Correlation: A Hospital Based Study

Cited by 7 publications

References 7 publications

Clinical profile and deformities in leprosy patients: a record based study

Clinical profile and deformities in leprosy patients: a record based study

A study of leprosy patients attended tertiary care hospital

Pattern and Complications of Leprosy among Patients attended Leprosy Clinic, Jesu Ashram, Siliguri, West Bengal: A 3 Years Record Based Study

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