Spectrum of lytic lesions of the skull: a pictorial essay

Ugga, Lorenzo; Cuocolo, Renato; Cocozza, Sirio; Ponsiglione, Andrea; Stanzione, Arnaldo; Chianca, Vito; D’Amico, Alessandra; Brunetti, Arturo; Imbriaco, Massimo

doi:10.1007/s13244-018-0653-y

Cited by 39 publications

(32 citation statements)

References 40 publications

(42 reference statements)

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“…Prognosis is good and the majority of patients are cured [23]. Patients may suffer local pain and swelling [21,24]. Skull lesions are typically well-defined and lytic, with sclerotic or non-sclerotic margins, and possible periosteal reaction.…”

Section: Eosinophilic Granulomamentioning

confidence: 99%

“…MRI shows a T2-hyperintense lesion with variable degrees of contrast enhancement, and possible bone and soft tissue edema ( Fig. 4) [21,24].…”

Section: Eosinophilic Granulomamentioning

confidence: 99%

“…The lesion can present with pain and eventually pathological fracture. It can be primary (arising de novo) or, in a few cases, secondary (associated in the skull with eosinophilic granuloma, fibrous dysplasia, osteoblastoma, or giant-cell tumor) [21,27].…”

Section: Aneurysmal Bone Cystsmentioning

confidence: 99%

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Imaging of skull vault tumors in adults

et al. 2020

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The skull vault, formed by the flat bones of the skull, has a limited spectrum of disease that lies between the fields of neuro-and musculoskeletal radiology. Its unique abnormalities, as well as other ubiquitous ones, present particular features in this location. Moreover, some benign entities in this region may mimic malignancy if analyzed using classical bone-tumor criteria, and proper patient management requires being familiar with these presentations. This article is structured as a practical review offering a systematic diagnostic approach to focal calvarial lesions, broadly organized into four categories: (1) pseudolesions: arachnoid granulations, meningo-/encephaloceles, vascular canals, frontal hyperostosis, parietal thinning, parietal foramina, and sinus pericrani; (2) lytic: fibrous dysplasia, epidermal inclusion and dermoid cysts, eosinophilic granuloma, hemangioma, aneurysmal bone cyst, giant cell tumor, metastasis, and myeloma; (3) sclerotic: osteomas, osteosarcoma, and metastasis; (4) transdiploic: meningioma, hemangiopericytoma, lymphoma, and metastasis, along with other less common entities. Tips on the potential usefulness of functional imaging techniques such as MR dynamic susceptibility (T2*) perfusion, MR spectroscopy, diffusion-weighted imaging, and PET imaging are provided.

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Section: Eosinophilic Granulomamentioning

confidence: 99%

“…MRI shows a T2-hyperintense lesion with variable degrees of contrast enhancement, and possible bone and soft tissue edema ( Fig. 4) [21,24].…”

Section: Eosinophilic Granulomamentioning

confidence: 99%

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Imaging of skull vault tumors in adults

et al. 2020

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“…However, myeloma is often accompanied by osteoporosis. Lytic lesions of the skull are also typical presentations of osseous epidermoid cysts, but the inner table is generally more affected than the outer table [ 20 ]. Skull destruction of metastatic tumors may also be accompanied by soft tissue masses, which are difficult to distinguish, especially in adults [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Radiologic findings that aid in the reduction of misdiagnoses of Langerhans cell histiocytosis of the bone: a retrospective study

et al. 2021

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Background This study aimed to identify the characteristic radiological signs for the diagnosis of Langerhans cell histiocytosis (LCH) of the bone. Methods We retrospectively studied 82 cases of LCH with bone lesions confirmed by pathology. Clinical and radiological features of the patients were analyzed. Results A total of 64 and 18 patients had single and multiple bone lesions, respectively. With regard to LCH with single bone lesions, 37.5% (24/64) of lesions were located in the skull and presented as bone destruction with or without soft tissue mass. The correct diagnosis rate of these lesions was 60.0% (9/15) in children and adolescents, but was only 22.2% (2/9) in adults. A total of 26.5% (17/64) of the solitary lesions were found in the spine. Of these, 88.2% (15/17) were located in the vertebral body and appeared to have different degrees of collapse, and 66.7% (10/15) of these lesions were correctly diagnosed. Of the unifocal lesions, 21.8% (14/64) were located in other flat and irregular bones and manifested as osteolysis. Only 21.4% (3/14) of these cases were correctly diagnosed. In total, 14.1% (9/64) of the isolated bone LCH lesions were located in the long bones. Of these, 77.8% (7/9) were located in the diaphysis and presented as central bone destruction with or without fusiform periosteal reaction and extensive peripheral edema, of which 42.9% (3/7) were correctly diagnosed before surgery or biopsy. With regard to LCH with multiple bony destructive lesions, 71.4% (10/14) of cases in children and adolescents were correctly diagnosed; however, all four cases among adults were misdiagnosed. Conclusion In all age groups, isolated diaphyseal destruction of the long bone with fusiform periosteal reaction and extensive peripheral edema, vertebra plana of the spine, and bevelled edge of skull defects accompanied by soft tissue masses strongly suggest LCH diagnosis. Moreover, the multiple bone osteolytic destruction in children and adolescents strongly suggests LCH diagnosis. Familiarity with these typical radiological signs of LCH is necessary to decrease misdiagnoses.

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“…A histiocitose de células de Langerhans é uma doença sistêmica rara, afetando principalmente crianças. O granuloma eosinofílico é uma de suas manifestações, geralmente consistindo em lesão osteolítica solitária em ossos chatos, especialmente o crânio (UGGA, et al, 2018).…”

Section: Histiocitoseunclassified

Hipertensão Arterial Sistêmica: Desenvolvimento De Material Educativo Para Serviços De Saúde

Einloft¹,

Araújo²,

Bayer³

et al. 2021

Políticas E Serviços De Saúde 3

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Direitos para esta edição cedidos à Atena Editora pelos autores.Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons.Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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Spectrum of lytic lesions of the skull: a pictorial essay

Cited by 39 publications

References 40 publications

Imaging of skull vault tumors in adults

Imaging of skull vault tumors in adults

Radiologic findings that aid in the reduction of misdiagnoses of Langerhans cell histiocytosis of the bone: a retrospective study

Hipertensão Arterial Sistêmica: Desenvolvimento De Material Educativo Para Serviços De Saúde

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