Spectrum of Magnetic Resonance Imaging Findings in Fungal Infections of Brain

Gupta, Kamini; Banerjee, Avik; Saggar, Kavita

doi:10.21276/ijcmsr.2018.3.2.33

Cited by 1 publication

(2 citation statements)

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“…Furthermore, the immunocompetent status of the patient posed a diagnostic dilemma and made fungal infection a less likely clinical diagnosis. Callosal involvement by CNS aspergilloma is rare but has been described; however, the symmetrical butterfly appearance in our case makes it unique [ 8 , 10 ].…”

Section: Discussionmentioning

confidence: 89%

“…With regards to the differentials of neoplasms of the anterior cranial fossa, lymphoma and meningioma have been described as mimickers of CNS aspergillosis [ 3 , 8 , 9 ]. Very rarely, a giant aspergilloma may infiltrate the corpus callosum and mimic a butterfly glioma, as stated in one study in our extensive literature search [ 10 ]. However, butterfly gliomas have infiltrative margins with areas of necrosis and are usually T2 hyperintense.…”

Section: Discussionmentioning

confidence: 99%

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Giant Central Nervous System Aspergilloma Mimicking Butterfly Neoplasm of the Corpus Callosum

Khandwala¹,

Mubarak²,

Minhas³

et al. 2022

Cureus

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Radiological presentation of central nervous system (CNS) aspergillosis is variable and depends on the immune status of the patients. Typical features of meningoencephalitis, infarction, abscess, and mycotic aneurysms commonly occur in immunocompromised patients. A rare mass-like or tumoral form of cerebral aspergillosis has been described mostly in immunocompetent patients which results in a diagnostic dilemma, thus potentially causing a delay in the management. We present a case of a large CNS aspergilloma mimicking an infiltrative callosal neoplasm in a young immunocompetent patient. Careful evaluation of imaging features, anatomical location, enhancement pattern, concomitant sinonasal and orbital extension, and angio-aggressive nature of the mass lesion with a high index of suspicion can help diagnose CNS aspergillosis in such patients.

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Section: Discussionmentioning

confidence: 89%