Spectrum of Transfusion Transmitted Infections Among Apparently Healthy Blood Donors in Blood Bank RIMS Ranchi From 2008 to 2014

Abstract

Context:Apparently healthy blood donors might carry out transfusion transmitted infections which might be fatal for the donor himself as well as the recipient later on. Aim: To assess the seroprevalence of transfusion-transmitted infections (TTI) among apparently healthy blood donors in Ranchi, India. Methods and Materials: All blood samples were screened for HIV-I and II, HBsAg, HCV (by using third generation enzymelinked immunoadsorbent assay technique), Syphilis (by Rapid Plasma Reagin Kit), and Malaria antigen both for plasmodium falciparum and plasmodium vivax (by One step, rapid, immunochromatographic test). Result: On screening of 106,306 blood units for TTIs, 1,462 (1.37 %) donors were found positive for one of the TTIs. Highest prevalence was for HBV (970 donors -0.91%) ranging from 0.73% to 1.19%. This was followed by Malaria (272 donors -0.25%) ranging from 0.08% to 0.48%, HCV (127 donors -0.11%) ranging from 0.04% to 0.25%, HIV (72 donors -0.06%) ranging from 0.03% to 0.10%, and syphilis (21 donors 0.01%) ranging from 0.00% to 0.09%. Conclusions: Apparently healthy blood donors are not omitted from the danger of transfusion-transmitted infection.