Spectrum of uterine lesions presenting as abnormal uterine bleeding in a rural north Indian population: a study from tertiary care center

Singh, Shruti; Pandey, Pinki; Agarwal, Savita; Kaur, Swaran; Singh, Sanjeev

doi:10.18203/2320-6012.ijrms20162274

Cited by 5 publications

(4 citation statements)

References 7 publications

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“…Similar results were reported in study by Sharma K et al which shows 62.19% cases of normal cyclical pattern [8] . Proliferative pattern is the dominant histological pattern in our study and it is comparable to the study by Singh S et al [9] . Disordered proliferative pattern (DPE) is characterised by the absence of uniform glandular development and resembles simple hyperplasia but it is focal in the process rather than diffuse [13] .…”

Section: Discussionsupporting

confidence: 92%

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Histopathological spectrum of endometrial biopsies in abnormal uterine bleeding: A one year experience in a tertiary care centre

Gupta¹,

Rani²,

Suri³

2021

Int. J. Clin. Diagn. Pathol.

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Background: Abnormal uterine bleeding (AUB) shows spectrum of patterns on histopathology and pathologist plays a very vital role in reporting of endometrial biopsies and helps in differentiating nonneoplastic lesion from neoplastic lesions, early detection of the precursor lesions and exclusion of malignancy. The aim of this study is to study the spectrum of endometrial patterns in women with AUB and to correlate it with the different age groups. Materials and Methods: 272 samples of endometrial biopsies with AUB were received from the gynaecology department, processed and stained with hematoxylin & eosin and subjected to histopathological examination. Results: The peak incidence is observed in the age group of 41-50 years. The most common histomorphological pattern is proliferative pattern. 66 cases (24.26%) show endometrial hyperplasia out of which 8cases show atypia. 6 cases of endometrial carcinoma were reported and most of them were present in postmenopausal age. Pill endometrium and chronic endometritis were not reported in postmenopausal age group and all 3 cases of atrophic endometrium were reported in postmenopausal age group. Conclusion: AUB significantly affects the quality life of women and leads to anemia. Hence histopathological examination should be considered which plays a critical role in early diagnosis of endometrial pathology and to provide appropriate gynaecological management.

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Section: Discussionsupporting

confidence: 92%

“…To diagnose the cause of AUB is of great importance as it leads to anemia and significantly affects the quality of life [7] . In our study of 272 cases, the peak incidence is seen among [8][9][10][11][12] . Histopathological examination of the endometrial biopsies shows spectrum of patterns in which normal cyclical pattern i.e.…”

Section: Discussionmentioning

confidence: 85%

Histopathological spectrum of endometrial biopsies in abnormal uterine bleeding: A one year experience in a tertiary care centre

Gupta¹,

Rani²,

Suri³

2021

Int. J. Clin. Diagn. Pathol.

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“…from Iraq and Bolde et al18 & Singh et al19 from India have also reported proliferative endometrium being more common histopahtological finding which is in compliance with that of our study results.…”

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confidence: 93%

Histopathological spectrum of endometrial lesions in cases of abnormal uterine bleeding at a Tertiary Care Hospital.

Naeem

Samad²,

Sartaj³

et al. 2020

TPMJ

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Objectives: To assess histological spectrum of endometrial lesions in abnormal uterine bleeding at a tertiary care hospital. Study Design: Cross Sectional study. Setting: Department of Pathology, Multan Medical & Dental College, Multan and Faisalabad Medical University, Faisalabad. Period: January, 2019 to December, 2019. Material & Methods: Using non – probability purposive sampling technique. Results: A total of 238 ladies presenting with abnormal uterine bleeding were registered in our study. Mean age of these patients with AUB was 47.25 ± 5.57 years (ranging 21 years to 59 years), 158 (66.4%) were aged more than 45 years. Eighty five (35.7%) were from rural areas while 153 (64.3%) from urban areas. Of these 238 females, 162 (68.1%) were illiterate and 76 (31.9%) were literate. Majority of patients i.e. 218 (91.6%) were married and mean duration of illness was 5.28 ± 3.89 months while 169 (71%) presented within 6 months of illness. Histopathological pattern revealed Proliferative phase endometrium was observed in 69 (29%), endometrial hyperplasia in 59 (24.8%), chronic endometritis in 40 (16.8%), secretory phase in 40 (16.8 %), atrophic endometrium in 30 (12.6%) and endometrial polyps in 10 (4.2%). Conclusion: Histological pattern revealed proliferative endometrium was commonest followed by hyperplasia, secretory phase and chronic endometrium in our study. Disordered proliferative endometrium was commonly observed in married females and those having duration of symptoms more than 6 months. Hyperplasia was more frequent in older patients who were married. Secretory phase was significantly more common in patients with prolonged disease and chronic endometritis was associated with marital status and prolonged disease duration.

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“…Owing to the impact of various hormonal, dietary, and environmental factors on the endometrium, it is susceptible to multiple pathological lesions [3]. Abnormal uterine bleeding (AUB) is a pattern that does not correspond to the amount, duration, or frequency of a normal menstrual cycle [4,5].…”

Section: Discussionmentioning

confidence: 99%

Endometrial Patterns Among Rural Women Undergoing Gynecological Procedures in a Tertiary Care Hospital

Vijayakumar¹

2023

Cureus

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IntroductionWomen with endometrial diseases often present in outpatient departments, and outpatient procedures easily enable diagnosis. Histopathological patterns vary with age, menstrual cycle, drug use, and pathological state. Teaching hospitals are often located away from rural areas. Materials and methodsAn ambispective study was performed over 33 months in a rural medical college hospital by perusing the histopathological registers of the department. Details of history and endometrial samples (biopsy and hysterectomy) were obtained using biopsy numbers and requisition forms. Functional and organic histopathology findings were manually entered into a spreadsheet, and statistics were performed using Statistical Package for the Social Sciences (SPSS) for Windows version 22 (IBM SPSS Statistics, Armonk, NY, USA). ResultsThere were 226 women, with total abdominal hysterectomies (TAH) performed in a significantly higher proportion of middle-aged women (range: 41-59 years). Of the middle-aged women, 70% presented with excessive menstrual bleeding, and a similar percentage of older women presented with uterovaginal (UV) prolapse. Hysterectomy specimens constituted most samples in this study. Proliferative endometrium was observed in 40% of patients and metaplasia (papillary syncytial, tubal, and squamous) in only 1.7%. Normal proliferative and secretory endometrium were observed in 91 (40.3%) and 41 (18.1%) patients, respectively. The presence of hyperplasia, decidualization, stromal breakdown, adenocarcinoma, adenomyosis, and endometrial polyps did not vary significantly among the three age groups (elderly, middle-aged, and young). ConclusionMost women in rural areas presented to the gynecologist with uterine bleeding; middle-aged women constituted most of those with gynecological complaints. Normal endometrium was observed in nearly half of the patients. Adenomyosis was the most common cause of uterine bleeding. Uterine endometrial malignancies were rare.

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Spectrum of uterine lesions presenting as abnormal uterine bleeding in a rural north Indian population: a study from tertiary care center

Cited by 5 publications

References 7 publications

Histopathological spectrum of endometrial biopsies in abnormal uterine bleeding: A one year experience in a tertiary care centre

Histopathological spectrum of endometrial biopsies in abnormal uterine bleeding: A one year experience in a tertiary care centre

Histopathological spectrum of endometrial lesions in cases of abnormal uterine bleeding at a Tertiary Care Hospital.

Endometrial Patterns Among Rural Women Undergoing Gynecological Procedures in a Tertiary Care Hospital

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