Sperm dondurma: Güncel gelişmeler

Erdemır, Fikret

doi:10.24898/tandro.2019.64597

Cited by 2 publications

(2 citation statements)

References 50 publications

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“…Mahmud Rami kışlasında kalırken asâkir-i şâhâne tabîb-i hâssası sıfatı ile onunla birlikte bulunmuş, bu sırada meydana gelen olayları Tarih-i Liva adıyla bir günlük halinde kaydetmiştir (8,10,13). Mustafa Behçet Efendi'nin başlamış olduğu, eski Şark hekimliği ile ilgili bazı folklorik bilgiler ihtiva eden, Hezar Esrar adındaki eseri yazmaya, ağabeyinin vefatından sonra 850. maddeden itibaren devam etmiştir, fakat onun da tamamlayamadığı eser ancak oğlu Hayrullah Efendi tarafından bitirilebilmiştir (13,23,24).…”

Section: Bulgular Abdülhak Molla'nın Hayatı Ve Eserleriunclassified

Abdulhak Molla and the beginning of smallpox vaccination at the Tibbiye

Kara

2023

Anadolu Kliniği Tıp Bilimleri Dergisi

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Amaç Hekimbaşı Abdülhak Molla’nın Türk tıbbının modernleşmesine katkıları ve Tıbbîye’de çiçek aşısı uygulamasının başlangıcı incelenmiştir. Gereç ve yöntemler Döneme ait temel kaynaklar ve konuyla ilgili monografiler taranarak karşılıklı okuma yapılmıştır. Bulgular Abdülhak Molla Türkiye’nin modernleşme yönünde kritik bir dönüşüm yaşadığı yıllarda üst seviyede görevlerde bulunmuştur. Şahsi özellikleri yanında çevresi ve özellikle Mustafa Behçet Efendi’nin kardeşi olması Molla’nın faaliyetlerinde rol oynamıştır. İki kardeş birbirini takip eden görevleri ve ortak vizyonları ile hem tıp eğitiminin hem de sağlık hizmetlerinin modernleşmesinde öncü bir kurum olan Tıbbîye’nin kuruluşunda rol oynamışlardır. Çiçek aşısı uygulamasının başlaması bu dönemde yaşanan dönüşümün sonuçlarını örneklendirmektedir. Tartışma ve sonuç Abdülhak Molla Türk tıp tarihine önemli ve belirleyici bir katkıda bulunmuştur.

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Section: Bulgular Abdülhak Molla'nın Hayatı Ve Eserleriunclassified

Abdulhak Molla and the beginning of smallpox vaccination at the Tibbiye

Kara

2023

Anadolu Kliniği Tıp Bilimleri Dergisi

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“…One of the reasons why sperm banks are rarely used in cancer patients is that some patients can regain spermatogenesis after treatments and natural conception has been reported to be 23-47% in these cases (16). Pregnancy rates achieved with frozen sperm vary between 12% and 35.2% (17).…”

Section: The Outcome Of Icsi Cycles Made With Thawed Spermsmentioning

confidence: 99%

Kanser hastalarında sperm kriyoprezervasyonu: 13 yıllık tecrübe

YÜKSEL,

ÖZAKŞİT,

ÖZDEMİR TAŞ

et al. 2023

Jinekoloji-Obstetrik Ve Neonatoloji Tıp Dergisi

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ABSTRACT Purpose: The study represents 13 years experience of sperm cryopreservation for different cancer types by researching the semen parameters, the use of frozen-stored samples in ART-ICSI (Assisted Reproductive Technologies-intracytoplasmic sperm injection) cycles, and their current storage status. Materials and Methods: Sperm cryopreservation in order to fertility preservation was conducted on 318 patients who had different malignancies applied to the Reproductive Center of Ankara Bilkent City Hospital (from November 2019 to April 2023) and Zekai Tahir Burak Women’s Health Hospital (from January 2010 to September 2019). The age, cancer type, semen volume, sperm count, sperm motility, samples storage status, and usage of banked sperm in ART cycles were recorded and analyzed. Results: Sperm cryopreservation was applied to a total of 318 patients for 13 years. The major cancer types of patients are testicular cancer (54.7%), lymphoma (17.3%), and leukemia (10.1%). 11% (n=35) of patients are under the age of 18 years old. The lowest sperm cryopreservation age at 14 years old in four patients. The highest median semen volume was detected in leukemia (3.1 (1.5-6.0)), and the lowest mean semen volume was in the urinary system tumor (1.5 (1.0-2.0)).In testicular cancer, the median(min-max) sperm concentration is 12.5 (1.0-100.0)×106/mL. In lymphoma, the median(min-max) sperm concentration is 40.0 (1.0-140.0)×106/mL. In leukemia, the median(min-max) sperm concentration is 24.5 (1.0-130.0)×106/mL. Sperm concentration significantly decreased in men with testicular cancer. The highest median of sperm motility was observed in nasopharyngeal tumor group (40.0 (20.0-60.0)). Compared to other cancer patients, individuals with leukemia (20.0 (2.0-55.0)) and urinary system tumors (8.0 (6.0-55.0)) showed lower sperm motility. Leukemia (20.0 (2.0-55.0)) The longest time of sexual abstinence was detected in leukemia 7.0 (1.0-25.0) and osteosarcoma (7.0 (3.0-10.0)). Four patients applied to our center to use their frozen sperm. The patients underwent five ART (ICSI) cycles and four embryo transfers. One of the patient had abnormal fertilization and one of the patient had twin clinical pregnancy. Three patients transferred their banked sperm to another center. Sperm samples of 277 patients continue to be stored in our fertility center. Conclusion: Since surgical methods, chemotherapy and radiotherapy treatments used for cancer treatment have intense negative effects on spermatogenesis and fertility health, sperm cryopreservation is the gold standard and increasingly being recommended in clinical practice for preserving the fertility potential of cancer patients before treatment.

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Sperm dondurma: Güncel gelişmeler

Cited by 2 publications

References 50 publications

Abdulhak Molla and the beginning of smallpox vaccination at the Tibbiye

Abdulhak Molla and the beginning of smallpox vaccination at the Tibbiye

Kanser hastalarında sperm kriyoprezervasyonu: 13 yıllık tecrübe

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