Sperm washing, use of HAART and role of elective Caesarean section

Semprini, E.; Vucetich, A.; Hollander, Lital

doi:10.1097/00001703-200412000-00005

Cited by 19 publications

(14 citation statements)

References 32 publications

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“…Por último, la estrategia de prevención de la TV se ha basado en la continua revisión de la evidencia acumulada, por lo que es de importancia seguir evaluando nuevas conductas tendientes a identificar en otros aspectos: la eventual inducción de resistencia y toxicidad de los antiretrovirales en la gestante como en el recién nacido y su potencial efecto en la calidad de vida posterior, la utilización de micronutrientes y su impacto en disminuir la TV, la indicación de la operación cesárea en gestantes con baja carga viral y el lavado espermático como elemento reductor de TV (21)(22)(23)(24)(25).…”

Section: Discussionunclassified

Vih/Sida: Comportamiento Epidemiológico De La Transmisión Vertical en El Contexto General De La Infección en Chile

et al. 2011

Rev. chil. obstet. ginecol.

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RESUMENAntecedentes: En embarazadas seropositivas sin profilaxis antirretroviral la transmisión vertical (TV) del VIH es de 30%, cifra que disminuye bajo al 2% con un manejo integral de prevención. Objetivo: Conocer el comportamiento epidemiológico de la TV en Chile desde la creación del programa nacional de prevención. Método: Datos aportados por el Departamento de Epidemiología del MINSAL y CONASIDA . Estudió de situación VIH/SIDA por año, regiones, grupo etario y sexo, con especial énfasis en TV. Resultados: Se notificaron 9.317 casos de VIH y 7.886 casos de SIDA , prevalencia en aumento hasta el 2003 con tendencia descendente posteriormente. La razón actual de VIH entre hombres y mujeres es de 4:1, con clara tendencia al aumento de notificación en mujeres. La principal vía de exposición sigue siendo la vía sexual (93,4%). El grupo más afectado está entre los 20-39 años (73,1% para VIH y 63,1% para SIDA), cabe destacar que entre 0-9 años se encuentra el 1,1% de los afectados por VIH y el 1,4% por SIDA, todos infectados por TV. Conclusiones: La transmisión vertical de VIH en Chile es responsable de un bajo porcentaje de las personas notificadas de VIH/SIDA, pero es la causa de la totalidad de los niños afectados por la infección en nuestro país. Se observa una importante reducción de la TV, llegando a niveles muy cercanos a los objetivos ministeriales.PALABRAS CLAVE: VIH, SIDA, transmisión vertical, embarazo SUMMARY Background:The risk of transmitting HIV from mother to unborn child, without any antiretroviral prophylaxis, reaches 30%. It can be reduced to less than 2% by implementing integral preventive strategies. Objective: To assess the epidemiological profile of HIV vertical transmission in Chile since the implementation of the national AIDS transmission prevention program. Method: Data from the Epidemiology Department of the Health Ministry and the National Commission for AIDS grouped by year, location, age and gender. With special emphasis on vertical transmission. Results: 9317 cases of HIV infection and 7886 cases of AIDS have been reported in Chile (1984Chile ( -2006, with a decreasing tendency since 2003. Sexual exposure continues to be the primary route with 93.4% of the cases. The male/female ratio for case notification is 4:1, with a rising tendency among women. The most affected is between 20-39 years old (73% HIV notification and 63.1% for AIDS). Among children between 0-9 years of age is 1.1% of the HIV and 1.4% of AIDS notifications, all of them for vertical transmission. Conclusions: HIV vertical transmission in Chile is responsible for a small percentage of HIV/AIDS notifications, but it accounts for all of the infected children. There's been an important reduction in this transmission route, reaching prevalence close to the aimed rates, which can explained by the expanding prevention programs of the health policies implemented by the Health Ministry.

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Section: Discussionunclassified

Vih/Sida: Comportamiento Epidemiológico De La Transmisión Vertical en El Contexto General De La Infección en Chile

et al. 2011

Rev. chil. obstet. ginecol.

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“…Sperm washing and assisted reproduction technologies have been proposed for HIV-discordant couples in order to minimize the chances of HIV transmission during conception attempts (Semprini 2004). In the first years of the HIV pandemic, reproductive guidelines strongly stated that HIV-infected patients should avoid pregnancy.…”

Section: B a C K G R O U N Dmentioning

confidence: 99%

“…There is relatively wide experience with the first two techniques in HIV-sero-discordant couples (Riley 2005). Semprini, et al have the largest experience with HIV-negative women undergoing IUI with sperm concentrates from HIV-infected male partners (Semprini 2004). No cases of horizontal HIV transmission were recorded after more than 4500 inseminations (Vernazza 2006).…”

Section: Description Of the Conditionmentioning

confidence: 99%

Sperm washing to prevent HIV transmission from HIV-infected men but allowing conception in serodiscordant couples

Eke¹,

Oragwu²

2010

Cochrane Database of Systematic Reviews

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“…Interventions in planned pregnancies between serodiscordant couples have recently been reported in the literature, using a variety of assisted reproduction technologies, including sperm washing, column purification and intracytoplasmic sperm injection with significant success in pregnancy outcomes and no transmission of HIV to mother or infant using washed sperm from fathers with HIV infection [19,20].…”

Section: Preconception Interventions To Preventmentioning

confidence: 99%

Update: Preventing mother-to-child transmission of HIV

Vogler

2006

Curr HIV/AIDS Rep

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The success of antiretroviral therapies for prevention of mother-to-child transmission of HIV in the developed world has prompted a wide array of research efforts, from improved implementation of voluntary counseling and testing programs to innovative approaches for short-course peripartum prophylaxis to understanding the dynamics of HIV transmission via breastfeeding. Clinical trials of modified short-course peripartum regimens which are applicable to resource-limited areas are demonstrating much lower transmission rates and preliminary data are emerging on limiting transmission via breastfeeding. Some of the most recent data on these topics are reviewed. Primary prevention of HIV in women of childbearing age combined with efforts to prevent mother-to-child transmission of HIV offer the best hope for addressing the burden of HIV in women and children.

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Sperm washing, use of HAART and role of elective Caesarean section

Cited by 19 publications

References 32 publications

Vih/Sida: Comportamiento Epidemiológico De La Transmisión Vertical en El Contexto General De La Infección en Chile

Vih/Sida: Comportamiento Epidemiológico De La Transmisión Vertical en El Contexto General De La Infección en Chile

Sperm washing to prevent HIV transmission from HIV-infected men but allowing conception in serodiscordant couples

Update: Preventing mother-to-child transmission of HIV

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