Sphaeranthus indicus: A Review of its Chemical, Pharmacological and Ethnomedicinal Properties

Makhija, I.K.; Richard, L.; Kirti, SP; Saleemullah, K; M., Jessy; Annie, Shirwaikar

doi:10.3923/ijp.2011.171.179

Cited by 15 publications

(6 citation statements)

References 8 publications

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“…38,39 A noticeably small amount of profitable phytochemical entities have entered on facts based therapeutics but hard works are still required to recognize bioactive molecules in herbal drugs. 40 The present investigation provides outline of up-to-date information on pharmacognostical and physico-chemical standardization of E. neriifolia leaves.…”

Section: Preparation Of Solution Of En6 Extract Fractionmentioning

confidence: 99%

Pharmacognostical and Physico-chemical Standardization of Euphorbia neriifolia Leaves

Mali¹,

Panchal²

2017

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Section: Preparation Of Solution Of En6 Extract Fractionmentioning

confidence: 99%

Pharmacognostical and Physico-chemical Standardization of Euphorbia neriifolia Leaves

Mali¹,

Panchal²

2017

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“…All the extracts of the drug were subjected to different tests for detecting the presence of various phytoconstituents present in the drug, which revealed the presence of steroids, carbohydrates, proteins, terpenoid, flavonoid, tannins, alkaloids, resin and saponin etc. all the active constituents have specific pharmacological effects and often used as medications 30,31 . The results of phytochemicals screening are represented in Table 2.…”

Section: Resultsmentioning

confidence: 99%

Physicochemical and Phytochemical Studies on Sphaeranthus indicus Linn. with HPTLC Fingerprinting

Garg¹,

Dwivedi²

2021

J. Drug Delivery Ther.

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Ayurveda, the oldest paradigm of health and healing known to the world, grew out of the Rishi tradition. The medical and research community is constantly seeking for new natural agents. Sphaeranthus indicus Linn. (Gorakhmundi, Family: Asteraceae), is widely used in Ayurvedic system of medicine to treat various diseases. The present investigation was designed to perform physicochemical and phytochemical analysis with HPTLC fingerprints of Sphaeranthus indicus (leave, flower, and stem) to establish the standard parameters of this herb. Different analytical parameters like extractive values, total ash, acid insoluble ash and water-soluble ash, moisture content, pH values of different parts of the drug were performed. Preliminary phytochemical screening was done to detect and quantify different active constituents such as alkaloids, flavanoids, proteins and total poly phenol using various analytical methods. Our preliminary data of phytochemical screening of the extracts revealed the presence of steroids, carbohydrates, proteins, terpenoid, flavonoid, tannins, alkaloids, resin and saponin. In the current study we established the HPTLC fingerprint of the extract using phytochemical standards. We believe that our study provides a substantial data for identification, purification, standardization, and phytochemical characterization of novel therapeutic compounds that can be used potential drug to combat various diseases for betterment of mankind. Keywords: Sphaeranthus indicus, Ayurveda, physicochemical, UV- Spectrophotometer, HPTLC

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“…The traditional uses of plant include treatment of nervous depression, skin diseases, leucoderma, jaundice, scabies and psoriasis. The phytochemical and pharmacological aspects of the plant have been reviewed in various papers [8][9][10][11]. Wrightia tinctoria (Roxb.)…”

Section: Fig 1: Overview Of Aspartate Pathway In Fungi Shows Enzymesmentioning

confidence: 99%

Phytocompounds from Sphaeranthus indicus and Wrightia tinctoria targeting fungal Aspartate pathway – An in silico evaluation

R¹

2015

abp

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Aspartate pathway is essential in bacteria, fungi and plants. Any block in the pathway is lethal to the organism. Microbial resistance towards the drug molecule and the side effects exhibited by the drugs are the key basis for searching novel antimicrobial compounds. Since ancient times, medicinal plants are serving as remedies for several diseases and as a source for variety of components. The present study aims on identifying the potential phytocompounds reported from Sphaeranthus indicus and Wrightia tinctoria that can inhibit the pathway enzymes viz., Aspartate kinase, Aspartate semialdehyde dehydrogenase, Homoserine dehydrogenase and Homoserine O-Acetyl transferase. The availability of literature for this pathway is very limited and this work would serve as basis for exploring unique antifungal targets in the future. Among the phytocompounds docked, the first five compounds showing least G. score value were considered. Docking studies conclude rutin, sphaeranthanoloide and chlorogenic acid as potent inhibitors that can be further studied for developing antifungal agents.

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Sphaeranthus indicus: A Review of its Chemical, Pharmacological and Ethnomedicinal Properties

Cited by 15 publications

References 8 publications

Pharmacognostical and Physico-chemical Standardization of Euphorbia neriifolia Leaves

Pharmacognostical and Physico-chemical Standardization of Euphorbia neriifolia Leaves

Physicochemical and Phytochemical Studies on Sphaeranthus indicus Linn. with HPTLC Fingerprinting

Phytocompounds from Sphaeranthus indicus and Wrightia tinctoria targeting fungal Aspartate pathway – An in silico evaluation

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