1986
DOI: 10.1159/000309702
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Sphäroidale Degeneration der Hornhaut

Abstract: This is a clinical, histopathological and electron microscopical study on the spheroidal degeneration of the cornea by means of 48 histologically verified cases. False clinical diagnoses are surveyed and the presumed mechanism of the development of spheroidal degeneration is discussed.

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“…Two affected individuals (II:3 and II:8) also showed perilimbal deposits suggestive of amyloid material, although confirmation would require a histopathological examination. 20 GDLD is normally associated with severe ocular morbidity and blindness. Visual rehabilitation is problematic, often requiring multiple surgical interventions, with a high rate of recurrence and continued visual decline.…”
Section: Discussionmentioning
confidence: 99%
“…Two affected individuals (II:3 and II:8) also showed perilimbal deposits suggestive of amyloid material, although confirmation would require a histopathological examination. 20 GDLD is normally associated with severe ocular morbidity and blindness. Visual rehabilitation is problematic, often requiring multiple surgical interventions, with a high rate of recurrence and continued visual decline.…”
Section: Discussionmentioning
confidence: 99%