Spike voltage topography in temporal lobe epilepsy

Asadi‐Pooya, Ali A.; Asadollahi, Marjan; Shimamoto, Shoichi; Lorenzo, Matthew; Sperling, Michael R.

doi:10.1016/j.jns.2016.05.032

Cited by 2 publications

(1 citation statement)

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“…In this scenario, the absence or paucity of interictal spikes in the scalp EEG in TLE could then be suggestive of medial TLE if the seizure semiology is compatible. On the other hand, IEDs on scalp EEG with maximal amplitude on anterior temporal and anterior temporo-basal channels are evocative of a temporo-polar origin, whereas IEDs with maximal amplitude within mid-temporal region evokes lateral temporal origin Moreover, amplitude mapping of interictal spikes is a way to improve non-invasive EEG localization (Asadi-Pooya et al, 2016). In this context, two different populations of IED have been identified in TLE: type 1 = dipolar with inferior temporal negativity and vertex positivity; type 2 = non-dipolar with a lateral temporal maximum.…”

Section: Interictal Scalp-eeg Recordings In Focal Epilepsiesmentioning

confidence: 99%

Focal epilepsies and focal disorders

Lagarde¹,

Bartolomei²

2019

Handbook of Clinical Neurology

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Electroencephalographic (EEG) investigations are crucial in the diagnosis and management of patients with focal epilepsies. EEG may reveal different interictal epileptiform discharges (IED: spikes, sharp waves). The EEG visibility of spike depends on the surface area of cortex involved (>10cm 2) and the brain localisation of cortical generators. Regions generating IED (defining the "irritative zone") are not necessarily equivalent to the seizure onset zone. Focal seizures are dynamic processes originating from one or several brain regions (generating fast oscillations and called "epileptogenic zone") before to spread to other structures (generating lower frequency oscillations and called "propagation zone"). Several factors limit the expression of seizures on scalp EEG, such as area involved, degree of synchronization and depth of the cortical generators. Different scalp EEG seizure onset patterns may be observed: fast discharge, background flattening, rhythmic spikes, sinusoidal discharge, or sharp activity but to a large extent EEG changes are linked to seizure propagation. Finally, in the context of presurgical evaluation, the combination of interictal and ictal EEG features is crucial to provide optimal hypothesis about the epileptogenic zone.

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Section: Interictal Scalp-eeg Recordings In Focal Epilepsiesmentioning

confidence: 99%