2008
DOI: 10.1227/01.neu.0000317398.93218.e0
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Spinal and Nucleus Caudalis Dorsal Root Entry Zone Operations for Chronic Pain

Abstract: Spinal and trigeminal NC DREZ operations are effective in the treatment of intractable pain syndromes, especially in traumatic brachial plexus avulsions, segmental pain after spinal cord injury, postherpetic neuralgia, topographically limited cancer pain, and atypical facial pain.

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Cited by 42 publications
(39 citation statements)
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“…The term ''neuropathic pain'' is not typically used to refer to pain following a traumatic UE nerve injury. Many of the outcome studies following nerve injury or surgery included only measures of physical impairment and return to work as a measure of function, [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] and the studies that did include the DASH 4,6,9 were published more recently.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The term ''neuropathic pain'' is not typically used to refer to pain following a traumatic UE nerve injury. Many of the outcome studies following nerve injury or surgery included only measures of physical impairment and return to work as a measure of function, [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] and the studies that did include the DASH 4,6,9 were published more recently.…”
Section: Discussionmentioning
confidence: 99%
“…The few studies that have reported pain predominantly included patients following brachial plexus nerve injuries. 15,26,27,[48][49][50][51][52][53][54] In these studies, traumatic injuries, root avulsions, and injuries proximal to the dorsal root ganglion were associated with more pain; surgical intervention and the timing of surgery relative to injury were identified as important factors in alleviating pain. These outcome studies reported pain intensity and frequency but did not include validated patient-report questionnaires to assess the impact of the pain or impairment on the patient.…”
Section: Outcome Measuresmentioning
confidence: 99%
“…In our reported case, a pain-free status of 80 months was achieved on the left, the formerly operated side, which seems to be beyond the reported pain-free survival range. In our previously reported series, 69% of patients reported satisfactory pain relief one year after DREZ lesioning (19). Furthermore, in two of our patients who were diagnosed with complex regional pain syndrome type I, a pain syndrome with no reported curative treatment, the DREZ operation was curative in one (71 months' follow-up) and provided satisfactory results in the other (44 months' follow-up) (17).…”
Section: █ Discussionmentioning
confidence: 57%
“…In some cases or over time, pharmacological and noninvasive treatments fail to reduce the pain or the treatment itself ignores its efficacy considering the side effects. In these situations, some treatment options like tractotomy-nucleotomy and nucleus caudalis dorsal root entry zone (DREZ) lesioning shine as valuable means of managing such intractable problems (19,43).…”
Section: █ Case Report History and Presentationmentioning
confidence: 99%
“…Lissauers’s tract either increases or inhibits incoming pain signals before they synapse in Rexed laminae 1, 2 and 5, thus modulating pain. The detailed anatomy of this circuit has been previously described [3,4,5,6]. …”
Section: Introductionmentioning
confidence: 99%