Spinal Chondrosarcoma: A Review

Katonis, Pavlos; Alpantaki, Kalliopi; Michail, Konstantinos; Lianoudakis, Stratos; Christoforakis, Z.; Tzanakakis, George N.; Karantanas, Apostolos H.

doi:10.1155/2011/378957

Cited by 62 publications

(68 citation statements)

References 52 publications

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“…A plain CT scan shows calcification in the shapes of rings and arcs. MRI shows low intensity signal on T1 weighted images and heterogeneous low & high signal intensity on T2 weighted images [4].…”

Section: Discussionmentioning

confidence: 97%

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Cervical Chondrosarcoma- Rare Malignancy: A Case Report

Merchant

Mohiyuddin

Rudrappa

et al. 2014

Indian J Surg Oncol

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Section: Discussionmentioning

confidence: 97%

“…It commonly affects the thoracic spine followed by cervical and lumbar spine [4]. Only 1-12 % of these cases are reported to occur in the head and neck region [5].…”

Section: Introductionmentioning

confidence: 99%

Cervical Chondrosarcoma- Rare Malignancy: A Case Report

Merchant

Mohiyuddin

Rudrappa

et al. 2014

Indian J Surg Oncol

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“…However, surgical treatment of spinal chondrosarcoma is particularly difficult as most tumors adhere to nerve roots and the great vessels. When all locations are considered, survival from chondrosarcoma is relatively high, at 87% after 5 years, but is considerably lower for pelvic, sacral and spinal locations, varying between 25% and 54% 5. En bloc resection with wide disease free margins provides the best results in local chondrosarcoma control, with reported rates of recurrence as low as 3-8% 6.…”

Section: Discussionmentioning

confidence: 99%

Recurrent primary lumbar vertebra chondrosarcoma: Marginal resection and Iodine-125 seed therapy

Ren

Song

Wang

2014

IJOO

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“…Neurological manifestation may be the result of nerve involvement. Femoral nerve, sciatic nerve and lumbosacral plexus are commonly affected [7] . Though pain is a consistent symptom its nature initially is not severe hence various papers have reported the time from pain to diagnosis of Chondrosarcoma to be between 18 to 20 months [8] .…”

Section: Introductionmentioning

confidence: 99%

Chondrosarcoma of bone: A retrospective study of surgical management of 30 cases

Phadke¹,

Khandekar²,

Naik³

2017

Int. J. Orthop. Sci.

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Background: Chondrosarcomas are tumors that predominantly consist of cartilage and account for approximately 25% of all bone sarcomas. These tumors are relatively resistant to chemo and radiotherapy. They are classified into conventional Chondrosarcomas, de-differentiated Chondrosarcoma, mesenchymal Chondrosarcoma, juxtracortical Chondrosarcoma and secondary Chondrosarcoma on the basis of histopathology and whether or not they have occurred in a previously benign cartilaginous lesion. They are further subdivided into low grade, intermediate grade and high grade Chondrosarcoma on the basis of cellularity, atypia and pleomorphism. The clinical features of Chondrosarcoma include dull aching pain especially during night time, neurological symptoms (due to nerve involvement) and pathological fractures. Diagnosis is done by imaging and histopathology. Surgery is the primary treatment and consists of complete and wide excision whenever possible. Chemo and radiotherapy has got a limited role. We conducted this retrospective study of 30 patients with Chondrosarcoma treated with uniform surgical protocol at our institution. Materials and Methods: After obtaining approval from institutional ethical committee we conducted a retrospective study of 30 patients diagnosed with chondrosarcoma. Since Chondrosarcomas are rare we searched for the patients records diagnosed with Chondrosarcoma and details were studied from case papers and patient examination during follow up. All patients had undergone surgical treatment of primary tumors. The various surgeries done in these patients included wide excision, Tikhoff-Linberg procedures, wide chest wall resections and hemipelvectomies depending upon the site and size of the tumors. Minimum follow up was 24 months. The data was tabulated and analyzed using SPSS 16.0 version software. Results: This study consisted of 30 patients having been diagnosed with Chondrosarcoma. There were 18 men and 12 women with a mean age of 34 years (range 18-50 years). The most common clinical features these patients presented with were swelling (76.66%) followed by pain (66.66 %), neurological symptoms due to nerve involvement (16.66%), fumigating skin lesion (13.33%) and pathological fractures (6.66%). Patients were diagnosed on the basis of Imaging (XRAY/CT /MRI) and biopsy followed by histopathological examination. Most common bones involved were femur (30%) followed by pelvic bones (26.67%) and humerus (13.33%). Various surgical procedures done included complete excision in 15 patients (50%) followed by Likhoff-Linberg procedure (20%), chest wall resections (16.66%) and hemipelvectomy (13.33%). 9 patients were lost to follow up. Out of remaining 21 patients 15 patients (50%) remained recurrence free during a follow up period of 24 months while 6 patients (20%) presented with either localized recurrence or metastasis. Conclusions : Chondrosarcomas are heterogeneous group of tumors ranging from low-grade to very aggressive, high-grade forms. In individuals presenting with localized disease wide s...

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Spinal Chondrosarcoma: A Review

Cited by 62 publications

References 52 publications

Cervical Chondrosarcoma- Rare Malignancy: A Case Report

Cervical Chondrosarcoma- Rare Malignancy: A Case Report

Recurrent primary lumbar vertebra chondrosarcoma: Marginal resection and Iodine-125 seed therapy

Chondrosarcoma of bone: A retrospective study of surgical management of 30 cases

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