2024
DOI: 10.1097/pas.0000000000002298
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Spinal Cord Astroblastoma With EWSR1-BEND2 Fusion in Female Patients

Lingyi Fu,
I. Weng Lao,
Liyun Huang
et al.

Abstract: Astroblastoma is an extremely rare central nervous system tumor characterized by astroblastic pseudorosettes and vascular hyalinization. Despite these histologic hallmarks, its morphology can vary, occasionally resembling other central nervous system tumors such as ependymoma. A novel tumor entity, astroblastoma, meningioma 1 (MN1)-altered, has been identified, featuring MN1 gene rearrangements typically involving BEN-domain containing 2 (BEND2) as a fusion partner. Most astroblastomas arise in the cerebral he… Show more

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