Spinal Cord Compression by Extradural Fat After Renal Transplantation

Steroid-induced Spinal Epidural Lipomatosis after Suprasella Tumor Resection

“…SEL was first reported by Lee et al11) in 1975. The first reported patient was using steroids after a renal transplantation.…”

Spinal epidural lipomatosis. Case report and review of the literature

“…Most reported cases have been patients receiving high-dose and/or prolonged glucocorticosteroid therapy (3). SEL is found in patients on steroid therapy for a wide range of diseases: rheumatoid arthritis (adult and juvenile forms), systemic lupus erythematosus, migratory polyarthritis, dermatomyositis, atopic dermatitis, polymyalgia rheumatica, chronic obstructive pulmonary disease, asthma, chronic active hepatitis, thyroid opthalmopathy, nephrotic syndrome, lymphoma and radiation pneumonitis, and in patients on steroid therapy follow-ing organ transplantation (2,. SEL caused by repeated epidural steroid injections for years has been described in a patient with erroneous diagnosis of multiple sclerosis (22).…”

“…Epidural lipomatosis is a well-recognized complication of excess exogenous glucocorticosteroids (1). Lee et al, in 1975, were the first to call attention to spinal epidural lipomatosis occurring in a patient receiving steroid therapy. They described a renal transplant patient who required laminectomy for spinal cord compression secondary to extradural fat (2).…”

Spinal cord compression secondary to idiopathic thoracic epidural lipomatosis in an adolescent: A case report and review of literature

“…Although rare, it has been suggested that the main cause of symptomatic SEL is the use of exogenous steroids, as first described by Lee et al [1], [2]. Since SEL causes compression on the spinal cord, it can produce symptoms that are indistinct from those of spinal stenosis and degenerative spine disease [1].…”