Spinal cord infarction: clinical and magnetic resonance imaging findings and short term outcome

Masson, Catherine

doi:10.1136/jnnp.2003.031724

Cited by 251 publications

(197 citation statements)

References 16 publications

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“…5 Our study limited the study population to paraplegic patients, as ASCIS occurs mostly in the midthoracic spinal cord. 2,3 For instance, Salvador de la Barrera et al 19 had 35 paraplegic subjects in their study population of 36 ASCIS patients. Another study 4 had 79% of the NLI located in the thoracic or lumbosacral region.…”

Section: Discussionmentioning

confidence: 99%

“…1 Most of these spinal cord infarctions are located in the thoracic or thoracolumbar spinal cord. [2][3][4] Although several predictors of outcome, such as age, gender and American Spinal Injury Association (ASIA) impairment scale, have been reported in patients with ASCIS, 4 only one study compared the neurological and functional outcome between patients with traumatic spinal cord injury (tSCI) or non-traumatic SCI with a solely vascular origin. 5 Iseli et al 5 identified that the rate of neurological and ambulatory recovery is quite similar in patients with tSCI and ASCIS.…”

Section: Introductionmentioning

confidence: 99%

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Is the outcome in acute spinal cord ischaemia different from that in traumatic spinal cord injury? A cross-sectional analysis of the neurological and functional outcome in a cohort of 93 paraplegics

et al. 2010

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Study design: Retrospective cohort study. Objectives: To compare the neurological outcome between paraplegic patients with acute spinal cord ischaemia syndrome (ASCIS) or traumatic spinal cord injury (tSCI) and to investigate the influence of SCI aetiology on the total Spinal Cord Independence Measure (SCIM)-II score. Setting: Level 1 trauma centre. Methods: Initial (0-40 days) and chronic-phase (6-12 months) American Spinal Injury Association (ASIA) sensory scores, lower extremity motor score (LEMS) and chronic-phase total SCIM-II scores were analysed. Differences between ASCIS and tSCI patients were calculated using Student's t-tests and Wilcoxon signed-rank tests. To assess which variables give rise to the prediction of total SCIM-II score, a multiple linear regression analysis was used. These predictor variables included complete (ASIA impairment scale A) or incomplete SCI (AIS B, C, and D), aetiology, age and gender. Results: Out of 93 included patients, 20 ASCIS and 73 tSCI patients were identified. In the complete SCI group, the initial pinprick scores were higher (Po0.05) in ASCIS patients compared with tSCI patients, 37.9 (95% Confidence Interval (CI), 23.3-52.5) and 27.3 (95% CI, 24.1-30.4), respectively. No other relevant differences in neurological outcome were identified between ASCIS and tSCI patients; however, the total SCIM-II scores were higher (Po0.05) in tSCI patients after 12 months. Using the linear regression analysis, we were able to predict 31.4% of the variability. The aetiology was not significant in this model. Conclusion: The neurological outcome was independent of the diagnosis ASCIS or tSCI. Furthermore, the diagnosis ASCIS or tSCI was not a significant predictor for total SCIM II scores after 12 months. Sponsorship: This study was granted by the 'Internationale Stiftung für Forschung in Paraplegie' (IFP), Zürich, Switzerland.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Is the outcome in acute spinal cord ischaemia different from that in traumatic spinal cord injury? A cross-sectional analysis of the neurological and functional outcome in a cohort of 93 paraplegics

et al. 2010

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“…This might be due to age-related processes affecting perfusion of the cord. The most common causes of spinal cord infarction in adults are vascular, including atherosclerosis, abdominal aortic disease/ surgery, and hypotension [6,[12][13][14][15][16][17]. Compromise of blood flow to the adult cord has also been associated with cervical spondylosis [18].…”

Section: Spinal Cord Infarctions Are More Commonly Reported In Adultsmentioning

confidence: 99%

“…This review included some children, but results were not reported with respect to age, cause or spinal cord region involved. Two series of adults with cord infarction found that outcome was poorer in patients with more profound disability at onset [12,16]. One follow-up study of 8 patients with cord infarction included two children: one had improvement in neurological function, and the other had deterioration [93].…”

Section: Outcome After Spinal Cord Infarctionmentioning

confidence: 99%

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Ischemic Spinal Cord Infarction in Children Without Vertebral Fracture

Nance

Golomb

2007

Pediatric Neurology

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Spinal cord infarction in children is a rare condition which is becoming more widely recognized. There are few reports in the pediatric literature characterizing etiology, diagnosis, treament and prognosis. The risk factors for pediatric ischemic spinal cord infarction include obstruction of blood flow associated with cardiovascular compromise or malformation, iatrogenic or traumatic vascular inujury, cerebellar herniation, thrombotic or embolic disease, infection, and vasculitis. In many children the cause of spinal cord ischemia in the absence of vertebral fracture is unknown. Imaging diagnosis of spinal cord ischemia is often difficult due to the small transverse area of the cord, cerebrospinal fluid artifact and inadequate resolution of MRI. Physical therapy is the most important treatment option. The prognosis is dependent on the level of spinal cord damage, early identification and reversal of ischemia, and follow-up with intensive physical therapy and medical support. In addition to summarizing the literature regarding spinal cord infarction in children without vertebral fracture, this review article adds two cases to the literature which highlight the difficulties and controversies in the management of this condition.

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Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody

et al. 2019

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Spinal cord infarction: clinical and magnetic resonance imaging findings and short term outcome

Cited by 251 publications

References 16 publications

Is the outcome in acute spinal cord ischaemia different from that in traumatic spinal cord injury? A cross-sectional analysis of the neurological and functional outcome in a cohort of 93 paraplegics

Is the outcome in acute spinal cord ischaemia different from that in traumatic spinal cord injury? A cross-sectional analysis of the neurological and functional outcome in a cohort of 93 paraplegics

Ischemic Spinal Cord Infarction in Children Without Vertebral Fracture

Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody

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