Spinal cord injury and degenerative cervical myelopathy

Satkunendrarajah, Kajana; Karadimas, Spyridon K.; Fehlings, Michael G.

doi:10.1016/b978-0-323-91532-8.00006-9

Cited by 3 publications

(4 citation statements)

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“…These factors contribute to poor secretion clearance, atelectasis, pulmonary infections, and respiratory failure, leading to prolonged mechanical ventilation, ventilator dependence, and increased morbidity and mortality. It has been reported that the average duration of the weaning process in cervical and high thoracic SCI patients is 37 days (Reyes et al, 2020; Satkunendrarajah et al, 2022).…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Respiratory complications, such as atelectasis, pneumonia, and respiratory failure, are frequently encountered among patients with cervical SCI. These complications contribute significantly to ventilator dependence and represent the primary cause of morbidity and mortality during both the acute and long-term phases (Satkunendrarajah et al, 2022;Tollefsen & Fondenes, 2012).Weaning from mechanical ventilation poses considerable challenges for patients with high complete SCIs, and prolonged weaning periods are associated with increased respiratory complications, mortality, and substantial health care costs, particularly for those presenting with severe hypoxemic respiratory failure (Füssenich et al, 2018). The management of airway and respiratory function is paramount in facilitating lung function restoration, preventing morbidity, and reducing mortality (Kornblith et al, 2013).To date, no intervention strategy has demonstrated efficacy in promoting accelerated pulmonary rehabilitation and rapid weaning for patients with severe hypoxemic respiratory failure following complete cervical SCIs.…”

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confidence: 99%

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A Fast-Track Respiratory Protocol for High Cervical Spine Injury: A Case Report

Pan,

Chen,

Zhou

2023

Journal of Trauma Nursing

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BACKGROUND: Cervical spinal cord injury can greatly affect pulmonary function, resulting in complications, including respiratory failure with prolonged mechanical ventilation, ultimately leading to increased mortality and high health care costs. Weaning from mechanical ventilation is particularly challenging in patients with complete high spinal cord injury. CASE PRESENTATION: We present the case of a 42-year-old man who suffered a complete cervical 5–6 spinal cord injury following a rollover motor vehicle crash and subsequently developed postoperative pneumonia and severe hypoxemic respiratory failure. He received a novel approach to fast-track respiratory care, including early and aggressive secretion clearance management, moderate pressure level of airway pressure release ventilation, timely transition to spontaneous mode, early tracheostomy and humane care, and high-flow oxygenation via tracheotomy after weaning off the ventilator. As a result, the patient experienced significant improvement in pulmonary function and was successfully liberated from the ventilator within a 2-week period. CONCLUSION: This case highlights the potential effectiveness of fast-track respiratory care in promoting lung function restoration and expediting liberation from mechanical ventilation in patients with severe hypoxemic respiratory failure following a complete cervical spinal cord injury. However, further research is warranted to validate these findings and expand our understanding in this area.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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A Fast-Track Respiratory Protocol for High Cervical Spine Injury: A Case Report

Pan,

Chen,

Zhou

2023

Journal of Trauma Nursing

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“…Pulmonary complications such as impaired breathing and infection (e.g. pneumonia) after SCI are well-documented and have detrimental effects on recovery, mortality, and morbidity [23,[35][36][37][38]. While paralysis of the respiratory muscles contributes to these complications, especially in individuals who suffer cervical SCI, impairments in tissue-resident pulmonary immunity also play a role.…”

Section: The Lungsmentioning

confidence: 99%

System failure: Systemic inflammation following spinal cord injury

DiSabato,

Marion,

Mifflin

et al. 2023

Eur J Immunol

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Spinal cord injury (SCI) affects hundreds of thousands of people in the United States, and while some effects of the injury are broadly recognized (deficits to locomotion, fine motor control, and quality of life), the systemic consequences of SCI are less well‐known. The spinal cord regulates systemic immunological and visceral functions, and this control is often disrupted by the injury resulting in viscera including the gut, spleen, liver, bone marrow, and kidneys experiencing local tissue inflammation and physiological dysfunction. The extent of pathology depends on the injury level, severity, and time post‐injury. In this review, we describe immunological and metabolic consequences of SCI across several organs. Since infection and metabolic disorders are primary reasons for reduced lifespan after SCI, it is imperative that research continues to focus on these deleterious aspects of SCI to improve life span and quality of life for individuals with SCI.This article is protected by copyright. All rights reserved

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Development and Validation of a Novel Nomogram for Predicting Mechanical Ventilation After Cervical Spinal Cord Injury

Liu,

Zhang

et al. 2024

Archives of Physical Medicine and Rehabilitation

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Spinal cord injury and degenerative cervical myelopathy

Cited by 3 publications

References 80 publications

A Fast-Track Respiratory Protocol for High Cervical Spine Injury: A Case Report

A Fast-Track Respiratory Protocol for High Cervical Spine Injury: A Case Report

System failure: Systemic inflammation following spinal cord injury

Development and Validation of a Novel Nomogram for Predicting Mechanical Ventilation After Cervical Spinal Cord Injury

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