Spinal Cord Proliferative Sparganosis in Taiwan: A Case Report

Lo, Yi-Ming; Chao, David; Yan, Shihao; Liu, H C; Chu, F L; Huang, Chen‐Yu; Chang, Tung-Yao

doi:10.1227/00006123-198708000-00020

Cited by 26 publications

(8 citation statements)

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“…It is caused by the larvae of the tapeworm genus Spirometra , whose definitive hosts are domestic and wild cats and dogs [11,14,16]. Human infections usually occur in the following 3 ways; drinking untreated water containing infected copepods; ingesting raw or inadequately cooked flesh of snakes, frogs, or birds infected with spargana; and applying the flesh of an infected frog as a poultice to a wound [18].…”

Section: Discussionmentioning

confidence: 99%

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Sparganosis Presenting as Cauda Equina Syndrome with Molecular Identification of the Parasite in Tissue Sections

et al. 2013

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A 52-year-old woman presented with lower back pain, progressive symmetrical paraparesis with sensory impairment, and sphincter disturbance. Magnetic resonance imaging (MRI) of the whole spine revealed multiple intradural extramedullary serpiginous-mass lesions in the subarachnoid space continuously from the prepontine to the anterior part of the medulla oblongata levels, C7, T2-T8, and T12 vertebral levels distally until the end of the theca sac and filling-in the right S1 neural foramen. Sparganosis was diagnosed by demonstration of the sparganum in histopathological sections of surgically resected tissues and also by the presence of serum IgG antibodies by ELISA. DNA was extracted from unstained tissue sections, and a partial fragment of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene was amplified using a primer set specific for Spirometra spp. cox1. After sequencing of the PCR-amplicon and alignment of the nucleotide sequence data, the causative agent was identified as the larva of Spirometra erinaceieuropaei.

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Section: Discussionmentioning

confidence: 99%

“…In rare cases, a sparganum involves the spinal cord, usually at the thoracic to lumbar levels [7-15]. To our knowledge, only 3 cases have been reported as sparganosis with cauda equina syndrome [11,14,16]. None of these cases were confirmed by molecular diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Sparganosis Presenting as Cauda Equina Syndrome with Molecular Identification of the Parasite in Tissue Sections

et al. 2013

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“…It is caused by larvae of the tapeworm genus Spirometra, whose definitive hosts are domestic and wild cats and dogs 1,6,11) . The disease usually involves the subcutaneous tissue or muscle of the chest, abdominal wall, or limbs.…”

Section: Discussionmentioning

confidence: 99%

Sparganosis in the Lumbar Spine : Report of Two Cases and Review of the Literature

Park

Kim

et al. 2011

J Korean Neurosurg Soc

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A 42-year-old man presented with a 2-year history of progressive perianal paresthesia and pain, prominent on defecation. On admission, constipation was so severe that he could not defecate without intermittent self-administered enema. He also complained urinary incontinence and erection failure. The motor power of all extremities was normal, but muscle atrophy was detected in both legs. He also showed decreased Achilles tendon reflexes and anal tone. There were no skin nodules or organomegaly. Blood analysis showed that neutrophils and eosinophils were in the normal ranges. He had a history of ingesting inadequately cooked frogs and snakes 40 years before the onset of perianal paresthesia.Magnetic resonance (MR) imaging showed multiple nodular mass-like lesions from the conus medullaris to the lower end of the thecal sac, and adhesion of the cauda equine (Fig. 1).

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“…The former is caused by Spirometra erinaceieuropaei and Spirometra decipiens in China16, Japan17, Korea1819, Taiwan20 and Thailand21 and Spirometra mansonoides in the USA22. The latter is caused by the more pathogenic and disseminating Sparganum proliferum , which is reported as occurring only sporadically in Japan23, Taiwan24 and Thailand25 and very rarely in Paraguay, Venezuela, and the USA2627. Spirometra species require two intermediate hosts for the completion of their life cycle.…”

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confidence: 99%

Rapid identification of nine species of diphyllobothriidean tapeworms by pyrosequencing

Thanchomnang

Tantrawatpan

Intapan

et al. 2016

Sci Rep

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The identification of diphyllobothriidean tapeworms (Cestoda: Diphyllobothriidea) that infect humans and intermediate/paratenic hosts is extremely difficult due to their morphological similarities, particularly in the case of Diphyllobothrium and Spirometra species. A pyrosequencing method for the molecular identification of pathogenic agents has recently been developed, but as of yet there have been no reports of pyrosequencing approaches that are able to discriminate among diphyllobothriidean species. This study, therefore, set out to establish a pyrosequencing method for differentiating among nine diphyllobothriidean species, Diphyllobothrium dendriticum, Diphyllobothrium ditremum, Diphyllobothrium latum, Diphyllobothrium nihonkaiense, Diphyllobothrium stemmacephalum, Diplogonoporus balaenopterae, Adenocephalus pacificus, Spirometra decipiens and Sparganum proliferum, based on the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene as a molecular marker. A region of 41 nucleotides in the cox1 gene served as a target, and variations in this region were used for identification using PCR plus pyrosequencing. This region contains nucleotide variations at 12 positions, which is enough for the identification of the selected nine species of diphyllobothriidean tapeworms. This method was found to be a reliable tool not only for species identification of diphyllobothriids, but also for epidemiological studies of cestodiasis caused by diphyllobothriidean tapeworms at public health units in endemic areas.

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Spinal Cord Proliferative Sparganosis in Taiwan: A Case Report

Cited by 26 publications

References 0 publications

Sparganosis Presenting as Cauda Equina Syndrome with Molecular Identification of the Parasite in Tissue Sections

Sparganosis Presenting as Cauda Equina Syndrome with Molecular Identification of the Parasite in Tissue Sections

Sparganosis in the Lumbar Spine : Report of Two Cases and Review of the Literature

Rapid identification of nine species of diphyllobothriidean tapeworms by pyrosequencing

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