“…Bicknell and colleagues 5 recommended a multimodality approach including revascularization of the intercostals arteries, left heart bypass, spinal cord cooling, CSF drainage, and ensuring mean arterial pressure >80 mm Hg. Likewise, Nobuyoshi and colleagues 6 described important strategies that reduced the risk of paraplegia, including maintenance of total blood flow to the spinal cord during aortic crossclamping, provision of maximum collateral blood flow, reduction of spinal nervous tissue oxygen demand, prolongation of ischemic tolerance of the spinal cord, and reduction of reperfusion injury.…”