Spinal Cord Stimulation for Relief of Chronic Pain in Vasospastic Disorders of the Upper Limbs

Robaina, Francisco; Domínguez, Manuel Fernández; Diaz, Manuel; Rodríguez, José Luis González; Vera, J.A. de

doi:10.1097/00132586-198910000-00042

Cited by 26 publications

(37 citation statements)

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“…The use of SCS in Raynaud's syndrome was first described in 1989 by Robaina et al, who observed good-to-excellent results in three patients with idiopathic Raynaud's disease (13). In 1994 Francaviglia et al (14) reported on 15 patients with Raynaud's phenomenon secondary to progressive systemic scleroderma who were treated with cervical SCS and followed up for 12 months to six years.…”

Section: Discussionmentioning

confidence: 99%

Spinal Cord Stimulation for Raynaud’s Syndrome: Long-Term Alleviation of Bilateral Pain With a Single Cervical Lead

Wolter

Kieselbach

2011

Neuromodulation: Technology at the Neural Interface

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Section: Discussionmentioning

confidence: 99%

Spinal Cord Stimulation for Raynaud’s Syndrome: Long-Term Alleviation of Bilateral Pain With a Single Cervical Lead

Wolter

Kieselbach

2011

Neuromodulation: Technology at the Neural Interface

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“…Proposals include: sympatholytic effect [14,19], segmental liberation of vasoactive substances, and activation of vasomotor centers in the brainstem and cerebellum [19], which has a competitive effect with CO 2 upon the mechanisms of cerebral blood-flow regulation [16]. Other factors could also be operating in the effect of SCS on loco-regional tumor blood-flow.…”

Section: Discussionmentioning

confidence: 99%

“…Spinal cord stimulation (SCS) is a minimally-invasive neurosurgical technique used to treat pain [12], peripheral vascular disease [13], vasospasm [14] and ischemic heart syndromes [15]. Increased cerebral blood-flow in non-cancer patients has been demonstrated using transcranial Doppler (TCD) [16], single photon emission computed tomography (SPECT) [17,18] and laser Doppler flowmetry [18,19].…”

Section: Introductionmentioning

confidence: 99%

Modification of loco-regional microenvironment in brain tumors by spinal cord stimulation. Implications for radio-chemotherapy

Clavo

Robaina

Valcarcel³

et al. 2011

J Neurooncol

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The effectiveness of radiotherapy and chemotherapy in high grade gliomas (HGG) depends on tumor micro-environment. We summarize our experience of the influence of spinal cord stimulation (SCS) on this micro-environment. Patients with HGG (n = 26) were assessed pre- and post-SCS, using: (1) Doppler in middle cerebral arteries (MCA) and (2) in common carotid arteries (CCA); (3) tumor blood-flow using single photon emission computed tomography (SPECT); (4) tumor-pO(2) (mmHg) using polarographic probes (eight tumor areas from five patients); and (5) tumor glucose metabolism using (18)F-fluoro-2-deoxyglucose ((18)FDG) positron emission tomography ((18)FDG-PET). Pre-SCS: tumor blood-flow was lower (P < 0.001) than peri-tumor areas and healthy contra-lateral areas. Tumor-pO(2) was lower (P < 0.042) than healthy tissue. Tumor glucose metabolism was higher than peri-tumor areas (P = 0.017) and healthy contra-lateral areas (P = 0.048). Post-SCS: there were increases in: MCA blood-flow (P ≤ 0.002), CCA blood-flow (P ≤ 0.013), tumor blood-flow (P = 0.033), tumor glucose metabolism (P = 0.027) and tumor-pO(2) (P = 0.022). The percentage of hypoxic values decreased (P = 0.007). SCS can modify tumor micro-environment. The potential usefulness of SCS in improving the effectiveness of radio-chemotherapy in HGG needs to be evaluated.

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“…When looking back at the progress that has been made [3] 171 7 y 52% with ≥ 50% relief; 60% would repeat Turner et al [19] 39 study meta-analysis 16 mo 59% with ≥ 50% relief Segal et al [22] 24 19 mo 83.3% of physicians reported good to very good relief; 70% of patients reported good to very good relief Kemler [23] 24 (randomized controlled trial) 6 mo Mean decrease in VAS score of 3.6 cm; 58% of patients had GPE score of 6 (much improved) Kumar et al [24] 12 41 mo 100% of patients with good (50% to 74% pain reduction) to excellent (75% to 100% pain reduction) long-term pain relief Robaina et al [25] 8 6 mo 88% of patients experienced good (> 75% pain reduction) to excellent (> 90% pain reduction) long-term pain relief over the past 30 years, it is very encouraging and hopefully a sign of what is to come. The low-risk profile, reversibility, and improving outcomes of SCS in patients previously felt to be without hope should energize practitioners to advance the modality.…”

Section: Discussionmentioning

confidence: 99%

Current and future trends in spinal cord stimulation for chronic pain

Deer¹

2001

Current Science Inc

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Spinal cord stimulation (SCS) is a reversible treatment for chronic pain that is gaining favor as a first-line therapy for many disease states. Because there are no addictive issues and no side effects systemically, the treatment is moving up the treatment continuum ladder. First used clinically in 1967, the procedure was used exclusively for failed back surgery syndrome. Over the past 30 years selection criteria, psychologic screening, and technology have improved. These advances have broadened the treatment options for many patients in pain. This review focuses on the selection, indications, techniques, new advances, complications, and outcomes involved with SCS. A review is provided for the treatment of radiculitis, failed back surgery syndrome, complex regional pain syndrome, peripheral neuropathies, pelvic pain, occipital neuralgia, angina, ischemic extremity pain, and spasticity. Technologic advances such as multi-lead and multi-electrode arrays are also discussed in regard to the impact these developments have on the clinical application of the therapy.

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Spinal Cord Stimulation for Relief of Chronic Pain in Vasospastic Disorders of the Upper Limbs

Cited by 26 publications

References 0 publications

Spinal Cord Stimulation for Raynaud’s Syndrome: Long-Term Alleviation of Bilateral Pain With a Single Cervical Lead

Spinal Cord Stimulation for Raynaud’s Syndrome: Long-Term Alleviation of Bilateral Pain With a Single Cervical Lead

Modification of loco-regional microenvironment in brain tumors by spinal cord stimulation. Implications for radio-chemotherapy

Current and future trends in spinal cord stimulation for chronic pain

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