Spinal Curvature in the Atlantic Silversides, Menidia menidia (Linnaeus), and the Atlantic Menhaden, Brevoortia tyrannus (Latrobe)

Austin, Herbert M.; Hickey, Clarence R.

doi:10.2307/1350886

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…Skeletal defects such as lordosis produced in the lead-treated embryos are also common abnormalities produced in fish by a variety of teratogens (Anderson & Battle, 1967;Battle & Hisaoka, 1952;Thomas, 1975). Fish with bent spines are also found occasionally in nature (Austin & Hickey, 1973). A condition similar to the curled position of the fry was observed in coho salmon by Gunstrom (1973).…”

Section: Discussionmentioning

confidence: 96%

Effects of heavy metals on development of the killifish, Fundulus heteroclitus

Weis

1977

Journal of Fish Biology

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When F. heteroclitus embryos were exposed to inorganic mercury at concentrations of 0.03 or 0.1 mg/l at the early blastula stage, the percentage of successful axis formation was reduced and a significant proportion of embryos developed cyclopia or intermediate conditions leading to cyclopia. Treatment at the late blastula stage reduced the severity of the defects. Embryos which developed in lead at concentrations of 1 and 10 mg/l were normal in appearance until hatching, at which time they exhibited lordosis or were unable to uncurl from the position they had while still inside the chorion. No significant effects of cadmium at concentrations up to 10 mg/l were noted.

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Section: Discussionmentioning

confidence: 96%

Effects of heavy metals on development of the killifish, Fundulus heteroclitus

Weis

1977

Journal of Fish Biology

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Methylmercury teratogenesis in the killifish, Fundulus heteroclitus

Weis

1977

Teratology

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Exposure of developing eggs of the killifish, Fundulus heteroclitus, to 0.03 or 0.04 mg/l of methylmercuric chloride resulted in a variety of abnormalities. Percentage of axis formation was reduced somewhat, and many embryos developed cyclopia or intermediate conditions leading to cyclopia, reflecting interference with induction of the forebrain. Defects in the cardiovascular system also appeared in the form of failure of the heart to differentiate properly into chambers. The heart was a thin, feebly beating tube, incapable of causing the blood to circulate. Other tissues, however, continued developing fairly normally, and embryos showed spontaneous movement comparable to controls. Embryos with severe cardiovascular or optic defects did not hatch. Upon hatching, some embryos which had previously appeared normal were found to have skeletal malformations in the form of vertebral bends or the inability to uncurl from the position which they had while still inside the chorion. Exposure to the toxicant for shorter periods of time (6, 12, or 24 hours) reduced the incidence of abnormalities. The second day of development was found to be the most sensitive period.

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Spinal Curvature in the Atlantic Silversides, Menidia menidia (Linnaeus), and the Atlantic Menhaden, Brevoortia tyrannus (Latrobe)

Cited by 2 publications

References 6 publications

Effects of heavy metals on development of the killifish, Fundulus heteroclitus

Effects of heavy metals on development of the killifish, Fundulus heteroclitus

Methylmercury teratogenesis in the killifish, Fundulus heteroclitus

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