Spinal epidural hematoma associated with warfarin therapy

Lederle, Frank A.; Cundy, Kara V.; Farinha, Pedro; McCormick, Daniel P.

doi:10.1016/s0002-9343(97)89465-x

Cited by 39 publications

(29 citation statements)

References 7 publications

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“…Some authors suggest the fragility of the epidural venous plexus as the cause of bleeding. Vascular malformations were proven in some cases, but their involvement is uncertain [8][9][10]. Gundry and Heithoff reported an association between epidural hematoma and rupture of a deep disc.…”

Section: Discussionmentioning

confidence: 99%

Posttraumatic thoracic anterior epidural hematoma together with Posttraumatic T11-12 Disc Herniation: A case report

Kayali¹,

H²

2017

Clin Case Rep Rev

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Section: Discussionmentioning

confidence: 99%

Posttraumatic thoracic anterior epidural hematoma together with Posttraumatic T11-12 Disc Herniation: A case report

Kayali¹,

H²

2017

Clin Case Rep Rev

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“…Compared to acute SSEHs, in which surgical decompression must be carried out rapidly,41112 in the rarer chronic SSEHs, the time before decompression procedures are undertaken does not seem to be critical for the recovery of neurological function and, finally, a good clinical outcome. Coz et al13 suggested that spreading of a hematoma remains possible until blood clotting has been completed.…”

Section: Discussionmentioning

confidence: 99%

Chronic spontaneous cervicothoracic epidural hematoma in an 8-month-old infant

Min

Duan

Jin

et al. 2011

Annals of Saudi Medicine

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Spontaneous spinal epidural hematoma is an uncommon cause of cord compression in children, especially in infants. An 8-month-old infant was admitted to our hospital for a 40-day history of paraparesis in the lower extremities. This rapidly progressed to paraparesis with an inability to move the lower extremities. MRI of the cervicothoracic spine revealed an epidural mass with compression of the spinal cord. The infant underwent C7-T3 total laminectomies. The pathology and postoperative MRI confirmed spinal epidural hematoma from a vascular malformation. We present the case to highlight the significance of recognizing this chronic spontaneous spinal epidural hematoma and discuss the diagnosis, treatment options and prognosis.

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“…[10][11][12] Unlike intracranial hemorrhage, bleeding in the spinal epidural space usually arises from the epidural veins and this fact may account for the silent interval between back pain and neurologic deterioration. 5) Incomplete preoperative sensorimotor deficit correlates highly with favorable outcomes, and recovery is significantly better when decompression is performed in ≤36 hours in patients with complete sensorimotor loss and in ≤48 hours in patients with incomplete sensorimotor deficit.…”

Section: Discussionmentioning

confidence: 99%

Spinal Epidural Hematoma Following Tissue Plasminogen Activator and Heparinization for Acute Myocardial Infarction.

Chan

Ueng

et al. 2002

Jpn Heart J

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SUMMARYThe case of a 43-year-old Taiwanese man who presented with spinal epidural hematoma following intravenous administration of recombinant tissue plasminogen activator (rTPA) and heparin therapy for acute myocardial infarction (AMI) is reported. Upper back pain and progressive neurological dysfunction ensued, secondary to spinal epidural hematoma with spinal cord compression. The patient did not recover neurologic function postsurgically, possibly because the operation was delayed. In conclusion, cardiologists should be alert to this rare, severe complication of rTPA and should perform early laminectomy (in ≤36 hours for those with complete deficit and in ≤48 hours for those with incomplete deficit) if possible. (Jpn Heart J 2002; 43: 417-421) Key words: Spinal epidural hematoma, Recombinant tissue plasminogen activator, Acute myocardial infarction THROMBOLYTIC therapy, in combination with heparin and aspirin, reestablishes coronary blood flow, reduces infarct size, improves left ventricular function, and reduces mortality following acute myocardial infarction (AMI). However, its use is limited by bleeding complications, especially intracranial hemorrhage. Spinal epidural hematoma associated with recombinant tissue plasminogen activator (rTPA) is very rare. We report here a case of spontaneous spinal epidural hematoma after combined rTPA and heparin therapy for AMI. CASE REPORTA 43-year-old Taiwanese man was admitted with acute inferior myocardial infarction. His coronary artery disease risk factors were smoking and uncontrolled hypertension. We administered thrombolytic therapy with recombinant From the

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Spinal epidural hematoma associated with warfarin therapy

Cited by 39 publications

References 7 publications

Posttraumatic thoracic anterior epidural hematoma together with Posttraumatic T11-12 Disc Herniation: A case report

Posttraumatic thoracic anterior epidural hematoma together with Posttraumatic T11-12 Disc Herniation: A case report

Chronic spontaneous cervicothoracic epidural hematoma in an 8-month-old infant

Spinal Epidural Hematoma Following Tissue Plasminogen Activator and Heparinization for Acute Myocardial Infarction.

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