Spinal Glioblastomas: Report of Seven Cases and Review of the Literature

Ciappetta, Pasquale; Salvati, Maurizio; Capoccia, Giovanna; Artico, Marco; Raco, Antonino; Fortuna, Aldo

doi:10.1227/00006123-199102000-00022

Cited by 99 publications

(57 citation statements)

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“…Intramedullary glioblastoma is uncommon in all ages of life, but in children are extremely rare. [6][7][8] Intramedullary glioblastoma shows a slight predilection for the second and third decades of life, the mean age ranging from 28.5 years in the 20-case series of the Mayo Clinic 9 to 18.1 years according to the review of the literature undertaken by Fortuna in 1971. 10 Our patient was a 6-year-old.…”

Section: Case Reportmentioning

confidence: 99%

“…This is consistent with previous studies of malignant spinal tumours. 6,11 Spinal cord glioblastomas occur mainly in the cervical or thoracic segments. 9,10,[12][13][14][15][16][17][18][19] In our case glioblastoma was localised at T 9 -T 11 .…”

Section: Case Reportmentioning

confidence: 99%

“…6,13,20,21 This can be explained by the proximity of the neoplastic cells to the cerebrospinal fluid pathways. 6,13,14 However, the possibility of surgical dissemination of glioblastoma through increased exposure of the subarachnoid spaces to the malignant glial cells cannot be excluded. 6,13 Also, the presence of multiple foci should be considered.…”

Section: Case Reportmentioning

confidence: 99%

“…6,13,14 However, the possibility of surgical dissemination of glioblastoma through increased exposure of the subarachnoid spaces to the malignant glial cells cannot be excluded. 6,13 Also, the presence of multiple foci should be considered. 6,10,13,14 Seeding of a spinal cord glioblastoma to the brain is extremely rare.…”

Section: Case Reportmentioning

confidence: 99%

“…These tumours occur mainly in the cervico-thoracic segments and have a short clinical history before diagnosis. 6 The aim of this paper is to report one case of a 6-year-old boy with intramedullary glioblastoma that spread to brain and to discuss the clinical, radiologic and therapeutic findings of these tumours with a review of the pertinent literature.…”

Section: Introductionmentioning

confidence: 99%

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Spinal glioblastoma with brain relapse in a child: clinical considerations

2005

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Case report: Spinal cord glioblastoma in children has only rarely been reported. It most frequently involves the thoracic region with a predilection for the second and third decades of life. This report describes one case of thoracic glioblastoma multiforme in a 6-year-old child and reviews other cases reported in the literature. Results: Laminectomy and excision of the tumour were performed. Postoperative radiotherapy and chemotherapy were given, but 4 months later the patient presented with a brain relapse of the tumour. At 9 months after diagnosis the patient died from cerebral tumour regrowth. Conclusions: Full neuraxis MRI is always recommended in order to detect possible metastases. The prognosis after multimodality therapy (surgery, radiotherapy, chemotherapy) remains poor. From the literature, only four cases of paediatric patients with long-term survival have been reported.

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Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Spinal glioblastoma with brain relapse in a child: clinical considerations

2005

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Prognostic factors in pediatric spinal cord astrocytoma

Bouffet¹,

Pierre-Kahn²,

Marchal³

et al. 1998

Cancer

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Spinal cord malignant astrocytomas

Santi

Mena

Wong

et al. 2003

Cancer

108

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Coupling a heterogeneous catalytic reaction with a membrane separation can solve the problem concerning catalyst separation in situ from the reaction mixture and make the production process continuous. In this article, the feasibility of continuous hydroxylation of phenol to hydroquinone (HQ) and catechol (CA) over ultrafine TS‐1 catalyst in a submerged ceramic membrane reactor system is investigated. It has demonstrated that the submerged ceramic membrane reactor system can maintain a steady production of HQ and CA, and has a higher productivity than the batch reactor and the fixed‐bed. The effects of operation conditions on the properties of the coupling process are examined by single factor experiments. Results show that the operation conditions influence greatly the conversion, selectivity of phenol hydroxylation, and the filtration resistance. The phenol conversion is above 17% and the dihydroxybenzene (DHB) selectivity keeps at about 90% in a 20 h continuous run under the optimal reaction condition. © 2008 American Institute of Chemical Engineers AIChE J, 2008

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Spinal Glioblastomas: Report of Seven Cases and Review of the Literature

Cited by 99 publications

References 0 publications

Spinal glioblastoma with brain relapse in a child: clinical considerations

Spinal glioblastoma with brain relapse in a child: clinical considerations

Prognostic factors in pediatric spinal cord astrocytoma

Spinal cord malignant astrocytomas

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