2018
DOI: 10.1080/20009666.2018.1472515
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Spinal gout causing reversible quadriparesis: a case report and literature review

Abstract: Gout commonly affects peripheral joints and is rarely found in axial joints, such as the spine and sacroiliac joints. We report a case of a patient that presented with quadriparesis who was empirically treated for spinal gout and a review of relevant literature. A 77-year-old male presented with new-onset quadriparesis that developed over 3 days. MRI imaging was suggestive of tophaceous gout of the cervical spine, but our patient refused a spinal biopsy. He was empirically treated with high-dose steroids and h… Show more

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Cited by 4 publications
(4 citation statements)
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“…[ 78 ] Several risk factors can contribute to hyperuricemia, including obesity, hypertension, chronic kidney disorders, alcohol consumption, high fructose or sucrose beverages, chronic kidney disease, and the use of organ transplantation or specific medications such as thiazides or loop diuretics. [ 52 ]…”
Section: Discussionmentioning
confidence: 99%
“…[ 78 ] Several risk factors can contribute to hyperuricemia, including obesity, hypertension, chronic kidney disorders, alcohol consumption, high fructose or sucrose beverages, chronic kidney disease, and the use of organ transplantation or specific medications such as thiazides or loop diuretics. [ 52 ]…”
Section: Discussionmentioning
confidence: 99%
“…La goutte chronique tophacée polyarticulaire est le quatrième et ultime stade évolutif de la maladie goutteuse [5]. Le 1er cas de goutte axiale fut décrit en 1950 par Kersley GD sur un cas autopsique de subluxation par érosion tophique de l'Atlas (C1) avec protrusion de l'Odontoïde dans le Foramen Magnum [6,7,8]. Koskoff YD et al décrivait 3 ans plus tard la première myélopathie goutteuse et Reynolds AF Jr en 1976, les 3 premiers cas neurochirurgicaux de goutte rachidienne par tophi flavo-ligamentaires (ligament jaune) compressifs [6], comme retrouvé dans nos 2 cas.…”
Section: Discussionunclassified
“…La localisation rachidienne et/ou spinale de cristaux d'urates en amas, appelé tophus, entouré d'une réaction inflammatoire est la définition princeps de la goutte spinale. Le tophus rachidien peut être unifocal ou pluriel à toutes les structures vertébrales et espaces intra et épidural [7,8]. Dans nos observations, les tophi étaient articulaires, ligamentaires et épiduraux.…”
Section: Discussionunclassified
“…Dual-energy CT can show the location and quantity of gout deposits. [2,5,12] But the gold standard for diagnosis of spinal gout is still monosodium urate crystallization pathology. Jegapragasant declared that for patients with lower back pain or nerve compression symptoms, spinal gout should be highly suspected if the patient has a history of gout, especially multiple nodules, hyperuricemia, and characteristic imaging changes.…”
Section: Discussionmentioning
confidence: 99%