Spinal osteoblastoma: relationship between paravertebral muscle abnormalities and scoliosis

Abstract

Nine patients had scoliosis. All patients with a thoracic or lumbar lesion and scoliosis (n = 8) had an associated abnormality of the paravertebral muscles (usually atrophy with fatty replacement). One patient with a lumbar lesion and no scoliosis had normal paravertebral muscles. One patient with a cervical lesion had thoracic scoliosis but no muscle abnormality in the cervical region, while two patients with cervical lesions and no scoliosis showed muscle abnormalities. The results support the clinical hypothesis that scoliosis in patients with spinal osteoblastoma is due to paravertebral muscle spasm, although this would not appear to be the case for cervical lesions.

Magnetic resonance imaging shows spinal curvature in Chinook salmon (Oncorhynchus tshawytscha) is associated with chronic inflammation of peri‐vertebral soft tissues

“…Unlike Type A, these lesions infiltrated the skeletal musculature, rather than being localized to the peri-vertebral connective tissues and associated septa, which has been previously observed in severely affected fish (Munday et al, 2016). This is consistent with Type B MRI signals representing a more advanced stage of the reparative process than Type A, as mature fibrosis is considered a 'hallmark' of chronic inflammatory response processes (Munday et al, 2016;Saifuddin et al, 1996).…”

“…In humans with scoliosis, the paravertebral muscle on the concave side of the curvature shortens, stiffens, and atrophies, but lengthens and hypertrophies on the convex side (Kim et al., 2013; Saifuddin et al., 1996). This may explain why Type A signal was consistently on the concave side of scoliotic, but not lordotic or kyphotic, curvatures.…”

Benign Osteoid-Producing Bone Lesions: Update on Imaging and Treatment

“…51 In addition, in cases where scoliosis has developed, the paraspinal muscles along the concave aspect of the curvature demonstrate various degrees of atrophy. 52 Secondary aneurysmal bone cysts with fluid-fluid levels may arise in 10% of osteoblastomas. 44 Periosteal osteoblastomas have a different appearance than the much more common intramedullary osteoblastomas.…”

Treatment of osteoblastoma at C7: a multidisciplinary approach. A case report and review of the literature

“…Ozaki et al reported scoliosis in 77% (17/22) of their patients, with an improvement seen in 16 of the 17 after tumor resection [15]. The tumors are found on the concavity of the scoliosis with a proposed etiology being muscle spasms secondary to inflammatory factors [18].…”