Spinal subarachnoid hemorrhage complicating oral anticoagulant therapy

Spinal subarachnoid haemorrhage complicating oral anticoagulation therapy

“…SSH is rare and accounts for 0.05-1.5% of cases of subarachnoid haemorrhage [2,3]. SSH is commonly caused by tumours, arteriovenous malformations (AVM) and aneurysms [4,5]. Other causes associated with SSH are bleeding disorders, anticoagulation therapy, vasculitis (systemic lupus erythematosus, Behcȩt's disease, polyarteritis nodosa), coarctation of the aorta and hypertension [5,6,7].…”

Drug interaction as cause of spontaneously resolving epidural spinal hematoma on warfarin therapy

“…[5] Intramedullary hematomas and subarachnoid spinal hemorrhages are also encountered during anticoagulant therapy though much rare. [67] Dorsal and lumbar areas are most commonly involved on anticoagulant therapy. [89] The most frequent entity of acute or chronic spinal hematoma is the spinal epidural variety.…”

Acute Painless Progressive Quadriplegia Associated With Warfarin Use

“…A review of Medline and reference lists of relevant papers revealed six previous reports of hematomyelia associated with oral anticoagulant use in the thoracic spinal cord 2–7 and three in the cervical cord 1,8,9 . Unlike this patient, all nine previous cases (aged 4–81) presented with a combination of pain and weakness.…”

“…The devastating complication of intracranial hemorrhage secondary to warfarin in the geriatric population is well documented, 1–9 but the incidence of spinal cord hemorrhage may be underrepresented. Given the widespread use of anticoagulants in older patients, progressive quadriparesis even in the absence of local neck pain or tenderness should prompt investigation for cervical lesions such as hematomas.…”