Spinal tuberculosis deserves a place on the radar screen.

McLain, Robert F.; Isada, Carlos M.

doi:10.3949/ccjm.71.7.537

Cited by 78 publications

(70 citation statements)

References 21 publications

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“…McLain et al 3 stated that spinal Tb mostly affects children in developing countries, in accordance with Francis et al 1 who also reported that spinal Tb is generally considered to be the disease of children in developing countries and of the elderly in developed ones. However the findings of the current study do not concur due to more adults being affected.…”

Section: Methodssupporting

confidence: 57%

“…McLain et al 3 reported that neurological deficits are common with long-standing thoracic and cervical involvement, and if untreated, neurological involvement may progress to complete and incomplete paraplegia. The results of our study indicate that 56% of our subjects presented with neurological deficits in which 24% had complete paraplegia and 32% incomplete paraplegia.…”

Section: Methodsmentioning

confidence: 99%

“…2 Skeletal involvement occurs in approximately 10% of all patients with extrapulmonary Tb. 3 The thoracic (42%) and lumbar (26%) regions are most affected with other regions less than 12% each. 4 South African (SA) provinces most severely affected by Tb are KwaZulu-Natal (KZN) and the Eastern Cape.…”

Section: Introductionmentioning

confidence: 99%

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Incidence and profile of spinal tuberculosis in patients at the only public hospital admitting such patients in KwaZulu-Natal

et al. 2008

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Study Design: A retrospective chart review at the major provincial public hospital serving patients with spinal injuries/pathology. Objectives and setting: To determine the incidence of spinal tuberculosis (Tb) and establish the profile of these patients treated at King George V Hospital (KGV) in KwaZulu-Natal, South Africa. Methods: A total of 525 medical records for the period March 2005 to April 2006 were reviewed. Data from 104 files of Tb spine cases were categorized according to demographic details, medical conditions and length of stay in hospital. The South African mid-year 2006 census was used to calculate associations and risk rates for race, gender, adulthood, urbanization and employment and analyzed using the STATA version 9.0 statistical package. Results: About 90% of the patients were African and 10% from other races. Females comprised 58% of the patients. The incidence of Tb spine is 1.02 per 100 000 and 3.13 per 100 000 for Africans and other races, respectively. The incidence rate is 1.17 per 100 000 females and 0.916 per 100 000 males. All the participants had a history of pulmonary Tb and 28% were human immunodeficiency virus positive. Thoracic spine was affected in 42% of the cases. About 32% presented with incomplete paraplegia. The average length of stay at this hospital for these patients was 41 days. Conclusions: About 20% of all patients seen for spinal conditions at KGV over the past year presented with Tb spine. A higher association between living in an urban area, adulthood (age 18 þ ), being nonBlack patients and the occurrence of spinal Tb was observed.

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Section: Methodssupporting

confidence: 57%

Section: Methodsmentioning

confidence: 99%

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Incidence and profile of spinal tuberculosis in patients at the only public hospital admitting such patients in KwaZulu-Natal

et al. 2008

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“…1 The thoracic spine is most frequently affected. 1 Patients commonly present with progressive pain, focal neurologic signs, and constitutional symptoms.…”

mentioning

confidence: 99%

“…1 The thoracic spine is most frequently affected. 1 Patients commonly present with progressive pain, focal neurologic signs, and constitutional symptoms. 2 On imaging, the relative sparing of the intervertebral disc, attributed to the absence of proteolytic enzymes in mycobacteria, and the presence of extensive soft tissue involvement distinguish Pott's disease from other infectious or malignant diseases of the spine.…”

mentioning

confidence: 99%