Spindle Cell Carcinoma of the Breast: Investigation of Magnetic Resonance Imaging Features of 26 Cases

Tokuda, Yukiko; Ko, Eun Sook; Yanagawa, Masahiro; Honma, Keiichiro; Shimazu, Kenzo; Tomiyama, Noriyuki

doi:10.1097/rct.0000000000001246

Cited by 2 publications

(4 citation statements)

References 31 publications

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“…Spindle cell carcinoma of the breast is a rare, aggressive form of breast cancer that accounts for 0.02-0.5% of all cases of invasive breast cancer in women [ 4 ]. Due to the aggressive nature of the disease, prompt diagnosis and treatment is necessary to achieve optimal outcomes for patients.…”

Section: Discussionmentioning

confidence: 99%

“…The MRI findings of spindle cell carcinoma of the breast were detailed in a series of 26 cases reported by Tokuda et al [ 4 ]. In this study, several radiologic features were common across the cases reported.…”

Section: Discussionmentioning

confidence: 99%

“…Spindle cell carcinoma of the breast is a subtype of metaplastic carcinoma characterized on pathology by spindle cell morphology with epithelioid differentiation [ 3 ]. It is exceedingly rare and accounts for 0.02-0.5% of cases of invasive breast cancer in the world [ 4 ]. Clinically, most cases present with a rapidly growing, palpable mass in the breast, ranging in size from 2-15 cm [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…Mammography typically shows an irregular mass with few cases showing evidence of calcification [ 8 ]. MRI findings typically include a round/oval solitary mass with central necrosis [ 4 ]. While rare, spindle cell carcinoma of the breast is an aggressive disease and prompt diagnosis and treatment is necessary to achieve optimal patient outcomes.…”

Section: Introductionmentioning

confidence: 99%

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A 52-Year-Old Woman Presenting With a Right Breast Mass: A Case Report

Frantz¹,

Hanna²

2022

Cureus

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We present the case of a 52-year-old female who presented with a rapidly enlarging right breast mass. An initial breast ultrasound showed a solid mass with cystic components and posterior acoustical enhancement and mammography showed a mass in the same area without calcifications. Biopsy of the lesion revealed spindle cell carcinoma of the breast. To date, the patient has undergone radiation therapy and simple mastectomy and will receive post-operative radiotherapy in the coming months.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A 52-Year-Old Woman Presenting With a Right Breast Mass: A Case Report

Frantz¹,

Hanna²

2022

Cureus

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A quantitative study to predict the risk of recurrence after radiotherapy for cervical cancer based on multi-sequence MRI imagingomics

Dai¹,

Lin

Lin³

et al. 2023

Preprint

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Background With the increasing clinical application of radiomics,the ability of magnetic resonance imaging omics to diagnose and predict the prognosis of diseases has attracted extensive attention in the scientific research community, and its application in the diagnosis, staging and treatment efficacy evaluation of cervical cancer has been gradually got attention..Methods All 52 patients in the radiotherapy group were cervical cancer patients and were diagnosed and treated with radiotherapy at our hospital from July 2019 to December 2021, while the healthy control group was selected from 41 healthy patients. The MRI performance of the two groups and the MRI performance of the patients in the radiotherapy group before and after treatment were observed separately. In addition, their ADC values were compared and the changes in ADC values before and after treatment were compared in patients with different prognosis in the radiotherapy group, compared the texture analysis parameters of patients with and without postoperative recurrence in radiotherapy group, and analyzed the predictive efficacy of MRI texture analysis parameters on the recurrence of cervical cancer patients after radiotherapy by ROC.Results The inorganic mass and DWI values of patients with cervical cancer increased with their grading and ADC decreased with them; Comparing the ADC values before and after radiotherapy, it was found that the values in the radiotherapy group were obviously lower than those in the healthy group (P < 0.05); a total of 16 patients (30.77%) received radiotherapy, they had recurrence within 6 months after radiotherapy and 36 patients (69.23%) had no recurrence in the radiotherapy group; according to the recurrence of patients after radiotherapy. The ROC curve analysis showed that the area under the curve of entropy value was the largest, which confirmed its diagnostic effectiveness.Conclusion Multi-series MRI imaging omics is of high clinical value in predicting the risk of recurrence after radiotherapy for cervical cancer patients.

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Spindle Cell Carcinoma of the Breast: Investigation of Magnetic Resonance Imaging Features of 26 Cases

Cited by 2 publications

References 31 publications

A 52-Year-Old Woman Presenting With a Right Breast Mass: A Case Report

A 52-Year-Old Woman Presenting With a Right Breast Mass: A Case Report

A quantitative study to predict the risk of recurrence after radiotherapy for cervical cancer based on multi-sequence MRI imagingomics

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