Spindle Cell Sarcoma of the Left Atrium: An Extremely Rare and Challenging Tumour Often Masquerading as Left Atrial Myxoma

Kholaif, Naji; O’Neill, Blair J.

doi:10.1016/j.cjca.2014.10.011

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…[4][5][6] However, intimal sarcomas that arise from the left atrium, as in our patient, have been reported infrequently. [7][8][9][10][11][12] Our patient's case illustrates the value of multimodal imaging in evaluating cardiac masses. The symptoms caused by cardiac tumors depend on their size, location, and degree of outf low obstruction; they often include dyspnea, chest discomfort, pericardial effusion, tamponade, and heart failure.…”

Section: A B C Dmentioning

confidence: 80%

Role of Multimodal Cardiac Imaging in Diagnosing a Primary Intimal Sarcoma of the Left Atrial Appendage

Raphael¹,

Martinez²,

Clements³

et al. 2019

Texas Heart Institute Journal

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Primary cardiac tumors are rare, and most are benign. Intimal sarcomas are among the rarest of the malignant cardiac tumors; they are aggressive and associated with a poor prognosis. Whereas transesophageal echocardiography has been instrumental in evaluating cardiac masses, other imaging methods, such as cardiac magnetic resonance, have proved invaluable in accurately characterizing these masses. We present the case of a 49-year-old woman in whom we diagnosed a primary intimal sarcoma of the left atrial appendage, and we discuss the importance of multimodal imaging in the evaluation and diagnosis of cardiac masses.

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Section: A B C Dmentioning

confidence: 80%

Role of Multimodal Cardiac Imaging in Diagnosing a Primary Intimal Sarcoma of the Left Atrial Appendage

Raphael¹,

Martinez²,

Clements³

et al. 2019

Texas Heart Institute Journal

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“…This is a highly diagnostic challenge when evaluating patients preoperatively due to nonspecific early clinical symptoms, the rarity of this tumor, and its echocardiographic resemblance to a cardiac thrombus. Primary cardiac malignancies occur more frequently in the right cardiac system, particularly the right atrium [Lau Under transthoracic echocardiography examination, cardiac sarcomas in the left-side cardiac lesion are often misdiagnosed as benign myxoma and thrombus organization [Kholaif 2015]. In this case, the patient had mitral valve stenosis, which explained his dyspnea; therefore, we discovered that the mass had a moderate texture and was tougher than myxoma and thrombus, indicating that malignant tumors should be suspected after opening the chest and heart.…”

Section: Discussionmentioning

confidence: 99%

“…Surgical resection remains the main treatment method for primary cardiac tumors. Surgical resection significantly improves survival relative to individuals who are not operated on [Kholaif 2015]. Patients who undergo complete tumor resection had an almost doubled life expectancy than those with incomplete excision [Reardon 2006].…”

Section: Discussionmentioning

confidence: 99%

Primary Osteosarcoma of Left Atrial Appendage in a Patient with Rheumatic Heart Disease

Zhang

Wei

Liu

et al. 2022

HSF

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Left atrial spindle cell sarcoma: a case report

Braams

Dengler

Rutten

et al. 2019

European Heart Journal - Case Reports

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Background Primary cardiac spindle cell sarcomas are extremely rare with only a few cases reported. They are frequently misdiagnosed on cardiac magnetic resonance (CMR) imaging as benign myxoma or thrombi and the suspicion of a malignant sarcoma arises only during surgery. This case report describes a case of cardiac spindle cell sarcoma diagnosed after surgery, where the initial diagnostic possibilities included an intramural thrombus and a cardiac myxoma. Case summary A 57-year-old woman was referred to our hospital for evaluation of a possible recurrent myxoma in the left atrium on echocardiography. Cardiac magnetic resonance imaging confirmed these masses as mural thrombotic masses, with a possible remnant of myxoma. After 2 months of anticoagulation therapy, the masses did not decrease in size on CMR imaging, and surgical removal was indicated. The atrial masses were surgically resected together with a large part of the left atrium. Histological examination showed spindle cell sarcoma. Unfortunately, the resection margins were positive and it was not possible to remove more atrium. PET-CT revealed metastasis in the right femur. The patient passed away 1 year after surgery. Discussion The rarity of spindle cell sarcoma and its similarities to benign cardiac myxoma and thrombi on echocardiography and CMR imaging present a diagnostic challenge when evaluating patients pre-operatively. Therefore, a malignant spindle cell sarcoma may only be diagnosed during surgery, after histological examination.

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Spindle Cell Sarcoma of the Left Atrium: An Extremely Rare and Challenging Tumour Often Masquerading as Left Atrial Myxoma

Cited by 4 publications

References 5 publications

Role of Multimodal Cardiac Imaging in Diagnosing a Primary Intimal Sarcoma of the Left Atrial Appendage

Role of Multimodal Cardiac Imaging in Diagnosing a Primary Intimal Sarcoma of the Left Atrial Appendage

Primary Osteosarcoma of Left Atrial Appendage in a Patient with Rheumatic Heart Disease

Left atrial spindle cell sarcoma: a case report

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