“…We found two systematic reviews presented in 5 articles [13][14][15][16][17]. Furthermore, we found 2 narrative reviews [10,18], 7 prospective cohort studies [19][20][21][22][23][24][25][26], 9 retrospective cohort studies often collecting data from medical records [27][28][29][30][31][32][33][34][35], and 8 case reports [36][37][38][39][40][41][42][43]. Six studies provided diagnostic test accuracy data related to red flags for detection of malignancy for patients with LBP and were included in the assessment of diagnostic accuracy using the QUADAS-2 (Table 1) [20,21,22,24,26,29].…”