Spiny keratoderma of the palms and soles – once seen, never forgotten

Painless Horny Keratotic Spines on the Palms: A Quiz

“…It was first described by Brown in 1971 (3) and numerous names can be used to describe this disease. Those include: punctuate porokeratosis, punctuate porokeratotic keratoderma, spiny keratoderma on the palms and soles, spiny keratoderma, palmoplantar filiform hyperkeratosis, filiform hyperkeratosis, music box dermatitis and minute digitate hyperkeratosis (2,(4)(5)(6)(7)(8).…”

“…As PK can precede malignancy by many years, regular follow-up should be scheduled according to age and personal risk factors (5,6).…”

“…Treatment can be challenging, as the disease may resurge if discontinued (6). Topical treatment with urea, salicylic acid, vitamin A or 5-fluorouracil cream or physical treatment, such as shaving or carbon dioxide laser vaporization, can be effective (5,6).…”

Spiny keratoderma

“…Dermatology Online Journal || Photo Vignette polycystic kidney disease, type IV hyperlipoproteinemia, and neoplastic diseases such as melanoma, leukemia, and lung, breast, and renal carcinomas [3]. This correlation is still unclear and could be coincidental because of the higher incidence of malignancy in patients over 50 years old [4].…”

İdiopathic palmoplantar filiform hyperkeratosis succesfully treated with systemic isotretinoin

“…görülen olgular da bildirilmiştir3,4 . FH'nin, bazı otörler tarafından paraneoplastik olduğu ve malignite oluşumundan önce değişen keratinizasyondan kaynaklandığı düşünülmüştür.…”