Spiral CT: how much does radiation dose matter?

Dixon, Adrian K.; Dendy, P P

doi:10.1016/s0140-6736(05)79751-8

Cited by 67 publications

(39 citation statements)

References 12 publications

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“…The effective dose of 16 mSv during a single CT scan is 5-fold more than during SBFT [20]. Although it is reported that a dose of 10 mSv is sufficient to cause fatal cancer in 1/2,000 patients [21], the long-term cumulative effect of this radiation is unknown and the extent of enhanced cancer risk remains controversial [22]. The most recent Australian population-based cohort study assessed the risk in children and adolescents following exposure to low-dose ionizing radiation from diagnostic CT. Out of 10.9 million people identified from Australian Medicare records between 1985 and 2005, all exposures to CT funded for people aged 0-19 were identified for the cohort.…”

Section: Radiation Exposure In Patients With CDmentioning

confidence: 99%

“…Typically, within 60 min prior to scanning a total of polyethylene glycol (PEG) is administered by dividing it into a plurality of times. Sensitivity ranges from 88 to 98% and specificity from 78 to 100%, respectively, for the detection of active inflammation [17,18,19,20,21,22,23,24,25,26,27,28,29,30,31]. MR enterography can be used to follow up and monitor disease activity and the effects of medical therapy such as immune-modulating agents, because it is free from radiation exposure and the discomfort associated with nasojejunal intubation.…”

Section: Mr Enterographymentioning

confidence: 99%

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Advancing Magnetic Resonance Imaging in Crohn's Disease

Fujii¹,

Kitazume

Saito³

et al. 2014

Digestion

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Crohn's disease (CD) is a lifelong chronic inflammatory bowel disease associated with diarrhea, abdominal pain, bloody stool and often perianal fistulae. Inflammation in CD involves the entire gastrointestinal tract, especially including the small and large bowels, causing irreversible bowel damage. Frequent imaging examinations are necessary to monitor disease activity and to evaluate response to therapeutic interventions, and, furthermore, to predict recurrence in order to provide appropriate treatment. The suitable imaging modality should be reproducible, well tolerated, safe and free of ionizing radiation. In recent years, imaging used in CD has dramatically changed. Cross-sectional imaging techniques such as computed tomography and magnetic resonance imaging (MRI) are used to investigate not only extraluminal abnormalities, but also intraluminal changes. Recently, new techniques such as MR enteroclysis, enterography, colonography and enterocolonography have been developed. These recent advances enable the use of MRI to assess bowel disorders with high sensitivity, specificity and accuracy. MRI can evaluate simultaneously the bowel surface, bowel wall, abdominal abscesses and perianal lesions, such as perianal fistulae and perianal abscesses, without the problem of overlapping bowel loops. Therefore, MRI has the potential for evaluation of the overall disease activity of CD without radiation exposure. We believe that MRI is a suitable first choice imaging modality in the assessment of CD.

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Section: Radiation Exposure In Patients With CDmentioning

confidence: 99%

Section: Mr Enterographymentioning

confidence: 99%

Advancing Magnetic Resonance Imaging in Crohn's Disease

Fujii¹,

Kitazume

Saito³

et al. 2014

Digestion

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show abstract

“…It is estimated that about 85% of a person's lifetime exposure to radiation will come from natural sources (background radiation) and about 15% will come from man-made sources. 11 The majority of manmade radiation will result from diagnostic radiology devices (about 97% from CT scanners).…”

Section: Estimated Exposurementioning

confidence: 99%

"Doctor, will that x-ray harm my unborn child?"

Ratnapalan¹,

Bentur²,

Koren³

2008

Canadian Medical Association Journal

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“…Effective doses may also be converted into a numerical risk of mortality from radiation-induced cancer (26), which is currently taken to be on the order of 5%/Sv when averaged over a whole population (5). The pediatric population represents an especially vulnerable group of individuals who are at increased risk for cancer (27). This fact is underscored 1 The equivalent dose (mSv) is the absorbed dose (mGy) multiplied by the radiation weighting factor wr, which depends on the type of radiation.…”

Section: Radiation Risksmentioning

confidence: 99%

Imaging strategies to reduce the risk of radiation in CT studies, including selective substitution with MRI

Semelka

Armao

Elias

et al. 2007

Magnetic Resonance Imaging

198

106

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“When one admits that nothing is certain one must, I think, also admit that some things are much more nearly certain than others.” Bertrand Russell (1872–1970) Computed tomography (CT) is one of the largest contributors to man‐made radiation doses in medical populations. CT currently accounts for over 60 million examinations in the United States, and its use continues to grow rapidly. The principal concern regarding radiation exposure is that the subject may develop malignancies. For this systematic review we searched journal publications in MEDLINE (1966–2006) using the terms “CT,” “ionizing radiation,” “cancer risks,” “MRI,” and “patient safety.” We also searched major reports issued from governmental U.S. and world health‐related agencies. Many studies have shown that organ doses associated with routine diagnostic CT scans are similar to the low‐dose range of radiation received by atomic‐bomb survivors. The FDA estimates that a CT examination with an effective dose of 10 mSv may be associated with an increased chance of developing fatal cancer for approximately one patient in 2000, whereas the BEIR VII lifetime risk model predicts that with the same low‐dose radiation, approximately one individual in 1000 will develop cancer. There are uncertainties in the current radiation risk estimates, especially at the lower dose levels encountered in CT. To address what should be done to ensure patient safety, in this review we discuss the “as low as reasonably achievable” (ALARA) principle, and the use of MRI as an alternative to CT. J. Magn. Reson. Imaging 2007;25:900–909. © 2007 Wiley‐Liss, Inc.

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Spiral CT: how much does radiation dose matter?

Cited by 67 publications

References 12 publications

Advancing Magnetic Resonance Imaging in Crohn's Disease

Advancing Magnetic Resonance Imaging in Crohn's Disease

"Doctor, will that x-ray harm my unborn child?"

Imaging strategies to reduce the risk of radiation in CT studies, including selective substitution with MRI

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