HOW CITED: Molina NPFM, Tavares DMS, Haas VJ, Rodrigues LR. Religiousity, spirituality and quality of life of elderly according to structural equation modeling. Texto Contexto Enferm [Internet]. 2020 [cited YEAR MONTH DAY]; 29: e20180468. Available from: http://dx.ABSTRACT Objective: to analyze the relationship of sociodemographic predictors, morbidities, depression indicative score, as well as the mediating role of religiosity, spirituality and personal beliefs about quality of life. Method: cross-sectional study conducted between March and July 2016, with 613 elderly, applying the instruments; Spirituality, Religiousness and Personal Beliefs of World Health Organization Quality of Life questionnaire, Brief version of World Health Organization Quality of Life questionnaire and World Health Organization Quality of Life Assessment for Older Adults.In the data analysis, through Statistical Package for Social Sciences, absolute and relative frequency, measures of central tendency and variability and modeling with structural equations involving exogenous and endogenous latent constructs were used to highlight the mediating role of religiosity, spirituality and beliefs between the indicative of depression and quality of life (p≤0.005). Results: females, 60┤70 years old, married, with 4├7 years of schooling, income of one minimum wage, 6.16±3.70 morbidities and average of 3.84±3.01 for the indicative depression score prevailed. The highest score was for the connection with spiritual being or strength facet, Social Relations domain and Intimacy; Totality and integration facet, the Environment domain and the Death and dying facet had the lowest scores. There was a mediating function of religiosity, spirituality and personal beliefs, between the indicative depression score and the quality of life. Conclusion: it is necessary to invest in the practice of religiosity, spirituality and personal beliefs, as a health strategy, since they have shown an impact on the decrease of depression and a significant increase in quality of life.Objetivo: analisar a relação de preditores sociodemográficos, morbidades, escore do indicativo de depressão, bem como o papel mediador da religiosidade, espiritualidade e crenças pessoais sobre a qualidade de vida. Método: estudo transversal realizado, entre março a julho de 2016, com 613 idosos, aplicando-se instrumentos Spirituality, Religiousness and Personal Beliefs of World Health Organization Quality of Life questionnaire, Brief version of World Health Organization Quality of Life questionnaire e World Health Organization Quality of Life Assessment for Older Adults. Na análise de dados, por meio do Statiscal Package for Social Sciences, utilizou-se frequência absolutas e relativas, medidas de tendência central e variabilidade e a modelagem com equações estruturais, envolvendo construtos latentes exógenos e endógenos para evidenciar o papel mediador da religiosidade, espiritualidade e crenças entre o indicativo de depressão e a qualidade de vida (p≤0,005). Resultados: prevaleceu o sexo femini...