Spirometric prediction equations and the relationship between metabolic syndrome and spirometric parameters from an island in <scp>F</scp>ujian, <scp>C</scp>hina

Chen, Yu‐Sheng; Li, Xiaoqin; Li, Hongru; Yu, Xinbing; Lu, Fengfeng; Huang, Liping; Yan, Miao; Wang, Guiqing; Lin, Xiao; Lin, Yun-Hua; Zhang, Xiange; Liu, Ting; Wu, Yanling

doi:10.1111/crj.12381

Cited by 5 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The ndings in our analysis are counter to studies looking at adult lung response to hypertension, which may be due to the age difference in the populations. A study conducted among 2,607 participants older than 30 years old residing in Fujian, China identi ed metabolic syndrome (OR: 4.623, 95% CI: 3.626, 5.894), which includes high blood pressure, as a risk factor for decreased lung function [29]. In a population-based study among 1,319 adults aged 40 to 65 years old, high blood pressure was associated with lowered FEV1 (P = 0.04) and FVC (P = 0.01) [30,31].…”

Section: Discussionmentioning

confidence: 99%

Association Between Blood Pressure And Lung Function In Chinese Children: The Seven Northeastern Cities Study

Huo

Yang

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: A global increase in asthma and COPD incidence has occurred, the cause is unknown. One potential relationship that has yet to be explored is the interaction between blood pressure (BP) and lung function in children 5-17 years old. Our purpose is to assess the relationship between hypotension, hypertension, and lung function in children 5 to 17 years old. Methods: Participants were recruited from elementary and middle schools from 7 cities in northeastern China (N=6,797). BP was categorized into 3 groups: hypotensive (<5th percentile or <90mmHg if children >10 years), normotensive and hypertensive (>95th percentile) based on American Academy of Pediatrics standards. Spirometry measured lung function in forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), peak expiratory flow (PEF), and maximum mid expiratory flow (MMEF). Associations were assessed using logistic regression analysis. Results: Decreases in FVC , FEV1, PEF, and MMEF were noted in hypotensive children. Higher FVC, FEV1, PEF, and MMEF were noted among children ³ 10 with hypertension, while children <10 years, only had increased FVC compared to normotensive children. Statistically significant interactions between hypotension and PEF < 75% (OR:2.31; 95% CI: 1.17-4.23), were seen for children < 10 years. Conclusions: Our findings suggest that, in this study population, hypotension may be associated with decreased lung function, and the increased lung function may be associated with hypertension in children. Future studies are needed to confirm temporality as this is the first study to explore these relationships in children which requires in depth investigation.

show abstract

Section: Discussionmentioning

confidence: 99%

Association Between Blood Pressure And Lung Function In Chinese Children: The Seven Northeastern Cities Study

Huo

Yang

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…There are studies showing decreased FVC in patients with MS ( 32 – 34 ) and an association between decreased FVC (L) and MS in a patient group ( 33 ). In a study recruiting 4001 adults, decreased FVC (L, %) was shown to be associated with each metabolic risk factor (waist circumference, systolic blood pressure, and serum triglyceride level) and MS ( 35 ).…”

Section: Discussionmentioning

confidence: 99%

Relationship between metabolic syndrome and epicardial fat tissue thickness in patients with chronic obstructive pulmonary disease.

et al. 2016

View full text Add to dashboard Cite

Objective:An increase in epicardial fat tissue (EFT) thickness was found to be associated with metabolic syndrome (MS) and ischemic heart disease. MS is a comorbidity of chronic obstructive pulmonary disease (COPD) resulting from the accompanying systemic inflammation. The aim of our study was to investigate the usefulness of EFT thickness to predict MS in COPD patients.Methods:COPD patients admitted to our clinic during January–December 2014 and healthy controls were included in this prospective case-control study. Patients with comorbidities, COPD exacerbation, and malignancies were excluded. Patients and controls were compared in terms of anthropometric measurements, MS-related examination and laboratory findings, pulmonary function tests, and EFT thickness. The correlations between EFT thickness and markers of MS in COPD were evaluated using the Student's t-test and logistic regression analysis.Results:COPD patients and controls were composed of 82 and 84 individuals, respectively. MS was diagnosed in 31 (37.8%) COPD patients. The EFT thickness was significantly higher in COPD patients than in the controls and was also higher in COPD patients with MS than in those without MS (all p<0.001). Each 1-mm increment of EFT raised the risk of MS two-fold (p=0.011, OR=2.08, 95% CI: 1.18–3.68). Increase in triglyceride level (p=0.004, OR=1.02, 95% CI: 1.01–1.03) and reduction in forced vital capacity (p=0.025, OR=0.26, 95% CI: 0.08–0.84) were found to be associated with increased MS risk. The cut-off value for EFT thickness in the prediction of MS in COPD patients was 6.75 mm (sensitivity: 83%, specificity: 65%).Conclusion:EFT thickness is a non-invasive and easily available parameter, which is valuable in the prediction of increased MS risk in COPD patients. Early diagnosis of patients at risk of MS may help to prevent ischemic heart disease in these patients.

show abstract

“…There are studies showing decreased FVC in patients with MS (32)(33)(34) and an association between decreased FVC (L) and MS in a patient group (33). In a study recruiting 4001 adults, decreased FVC (L, %) was shown to be associated with each metabolic risk factor (waist circumference, systolic blood pressure, and serum triglyceride level) and MS (35).…”

Section: Discussionmentioning

confidence: 99%

Relationship between metabolic syndrome and epicardial fat tissue thickness in patients with chronic obstructive pulmonary disease

Demir¹

2016

Anatol J Cardiol

View full text Add to dashboard Cite

Relationship between metabolic syndrome and epicardial fat tissue thickness in patients with chronic obstructive pulmonary disease Objective: An increase in epicardial fat tissue (EFT) thickness was found to be associated with metabolic syndrome (MS) and ischemic heart disease. MS is a comorbidity of chronic obstructive pulmonary disease (COPD) resulting from the accompanying systemic inflammation. The aim of our study was to investigate the usefulness of EFT thickness to predict MS in COPD patients. Methods: COPD patients admitted to our clinic during January-December 2014 and healthy controls were included in this prospective casecontrol study. Patients with comorbidities, COPD exacerbation, and malignancies were excluded. Patients and controls were compared in terms of anthropometric measurements, MS-related examination and laboratory findings, pulmonary function tests, and EFT thickness. The correlations between EFT thickness and markers of MS in COPD were evaluated using the Student's t-test and logistic regression analysis. Results: COPD patients and controls were composed of 82 and 84 individuals, respectively. MS was diagnosed in 31 (37.8%) COPD patients. The EFT thickness was significantly higher in COPD patients than in the controls and was also higher in COPD patients with MS than in those without MS (all p<0.001). Each 1-mm increment of EFT raised the risk of MS twofold (p=0.011, OR=2.08, 95% CI: 1.18-3.68). Increase in triglyceride level (p=0.004, OR=1.02, 95% CI: 1.01-1.03) and reduction in forced vital capacity (p=0.025, OR=0.26, 95% CI: 0.08-0.84) were found to be associated with increased MS risk. The cutoff value for EFT thickness in the prediction of MS in COPD patients was 6.75 mm (sensitivity: 83%, specificity: 65%). Conclusion: EFT thickness is a non-invasive and easily available parameter, which is valuable in the prediction of increased MS risk in COPD patients. Early diagnosis of patients at risk of MS may help to prevent ischemic heart disease in these patients.

show abstract

Spirometric prediction equations and the relationship between metabolic syndrome and spirometric parameters from an island in Fujian, China

Abstract: MS is a risk factor for decreased lung function in island residents ≥30 years old.

Cited by 5 publications

References 17 publications

Association Between Blood Pressure And Lung Function In Chinese Children: The Seven Northeastern Cities Study

Association Between Blood Pressure And Lung Function In Chinese Children: The Seven Northeastern Cities Study

Relationship between metabolic syndrome and epicardial fat tissue thickness in patients with chronic obstructive pulmonary disease.

Relationship between metabolic syndrome and epicardial fat tissue thickness in patients with chronic obstructive pulmonary disease

Contact Info

Product

Resources

About