Spitz Nevi

Tlougan, Brook E.; Orlow, Seth J.; Schaffer, Julie V.

doi:10.1001/jamadermatol.2013.1124

Cited by 50 publications

(8 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinical and dermatoscopic follow-up was the first choice in 6 pediatric patients under 12 years of age with lesions classified as typical Spitz/Reed nevi on clinical and dermatoscopic grounds, and an involution pattern was observed in more than half of the cases along 6 to 24 months, supporting an observational initial approach with clinical and dermatoscopic follow-up of Spitz/Reed nevi in young children, in accordance with other authors [ 7 , 8 ].…”

Section: Discussionsupporting

confidence: 86%

See 1 more Smart Citation

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

Pedrosa

Lopes

Azevedo

et al. 2016

Dermatol Pract Concept

View full text Add to dashboard Cite

Background:Spitz/Reed nevi are melanocytic lesions that may mimic melanoma at clinical, dermatoscopic and histopathological levels. Management strategies of these lesions remain controversial.Objectives:We aim a correlation among clinical-dermatoscopic and histological features of a series of Spitz/Reed nevi diagnosed during 7 years at the Department of Dermatology.Methods:Clinical, dermatoscopic and histological features of Spitz/Reed nevi diagnosed at our tertiary hospital from 2008 to 2014 were reviewed in order to seek correlation.Results:All described dermatoscopic patterns for Spitz/Reed nevi were found among the 47 enrolled patients; starburst and atypical/multicomponent patterns prevailed (57.4%). Reticular pattern predominated among children younger than 12 years, whereas homogeneous pattern was more frequent in patients older than 12 years, although these differences were not statistically significant (P=0.785). Among histological atypical lesions, all dermatoscopic patterns were represented, but the atypical/multicomponent predominated (56.3%). Two out of 11 dermatoscopically atypical lesions did not show histopathological counterpart.Conclusions:The excision of Spitz/Reed nevi in adults is supported, given the inability to accurately predict those with histopathological atypia, based on clinical and dermatoscopic features, which may raise concern about malignancy.

show abstract

Section: Discussionsupporting

confidence: 86%

“…Despite the attempts, there is no consensus in the histopathological classification of these lesions [ 7 , 8 ]. Although considered by some authors [ 3 ] an exclusively spindle-cell nevus, Reed nevus may display a mixed pattern with epithelioid and spindle cells.…”

Section: Introductionmentioning

confidence: 99%

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

Pedrosa

Lopes

Azevedo

et al. 2016

Dermatol Pract Concept

View full text Add to dashboard Cite

show abstract

“…Just like other authors, 12 , 13 we conclude that typical lesions may be followed up, even though the characteristics found in this case suggest a typical lesion because of its regular borders, size well below 10 mm, non-malignant aspect, and the possibility of regression with aging. The protocol of surgical excision with safety margins, histological analysis and recurrence monitoring was the therapeutic choice to decrease expectations of sudden growth and minimize the risk of trauma in the area, thus improving aesthetics by removing the visible lesion.…”

Section: Discussionsupporting

confidence: 86%

A Rápida Evolução Clínica De Um Nevo De Spitz: Acompanhamento De Três Anos Em Criança

Pedrazini

Montalli

Souza

2017

Rev. paul. pediatr.

View full text Add to dashboard Cite

Objective: To report the clinical evolution and handling of a Spitz nevus, from its initial flat feature to becoming an irregular, nodular, reddish lesion.Case description: Female child, phototype II, with a small congenital nevus on the left lower limb and other sustained small nevi. The patient went through annual clinical and dermoscopic evaluations between the ages of three and seven, period during which the nevi located on the left thigh grew rapidly. The clinical hypothesis was Spitz nevus, with indication of surgical removal with a safety margin and anatomopathological study. Considering patient’s age and clinical/histological aspects, the diagnosis of Spitz nevus was confirmed. Comments: Initial globular pattern and size under 5 mm upon dermoscopy allowed clinical follow-up. However, onset of hyperchromia and rapid growing of the lesion, along with aesthetic concerns, possibility of trauma in the region, and risk of malignancy at puberty guided the decision of total resection and follow-up for recurrence.

show abstract

“…In children with a clinical diagnosis of Spitz nevus, the option of clinical follow-up was chosen by 49.3% of respondents in the context of small, stable, non-pigmented lesions and by 29.7% in the context of pigmented lesions with a typical starburst pattern on dermoscopy. 26 Thus, pigmented lesions, even if exhibiting a typical starburst pattern, seemed to be of most concern to the majority of respondents.…”

Section: Discussionmentioning

confidence: 95%

“…Conservative management of Spitz nevi in children is increasing, as highlighted by a survey recently published. 26 In this study, respondents included 175 pediatric dermatologists from the United States and around the world, with about 80% utilizing dermoscopy. In children with a clinical diagnosis of Spitz nevus, the option of clinical follow-up was chosen by 49.3% of respondents in the context of small, stable, non-pigmented lesions and by 29.7% in the context of pigmented lesions with a typical starburst pattern on dermoscopy.…”

Section: Discussionmentioning

confidence: 99%

Clinical and dermoscopic features of atypical Spitz tumors: A multicenter, retrospective, case-control study

Moscarella

Lallas

Kyrgidis

et al. 2015

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

Background Few studies have described the clinical and dermoscopic features of atypical Spitz tumors (AST). Objective To describe the clinical and dermoscopic features of a series of AST as compared to those of conventional Spitz nevi (SN). Methods Multicenter, retrospective, case-control study, analyzing the clinical and dermoscopic characteristics of 55 AST and 110 SN that were excised and diagnosed histopathologically. Results The majority of AST presented clinically as a plaque or nodule, dermoscopically typified by a multicomponent or nonspecific pattern. A proportion of lesions (16.4%) exhibited the typical non pigmented spitzoid pattern of dotted vessels and white lines under dermoscopy. Nodularity, ulceration, linear vessels, polymorphic vessels, white lines, and blue/white veil were associated with AST by univariate analysis, but only nodularity and white lines remained significant after multivariate analysis. In contrast, a pigmented typical spitzoid pattern was a potent predictor of SN, associated with 6.5-fold increased probability. Limitations Differentiation from spitzoid melanoma and other non melanocytic lesions was not investigated. Conclusion Atypical Spitz tumors are polymorphic melanocytic proliferations with a nodular clinical appearance. Dermoscopically they demonstrate a multicomponent and nonspecific pattern. A typical non pigmented spitzoid pattern on dermoscopy (with dotted vessels and white lines) does not exclude AST.

show abstract

Spitz Nevi

Abstract: The results of our survey support conservative management of Spitz nevi in children, with clinical follow-up representing an option for typical lesions. This represents an important difference from strategies used for management of these lesions in adults.

Cited by 50 publications

References 56 publications

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

A Rápida Evolução Clínica De Um Nevo De Spitz: Acompanhamento De Três Anos Em Criança

Clinical and dermoscopic features of atypical Spitz tumors: A multicenter, retrospective, case-control study

Contact Info

Product

Resources

About