Splanchnic Uptake and Release of Energy Substrates in the Fasting Baboon Infant

Levitsky, Lynne L.; Paton, John B; Fisher, David E.; Delannoy, Clarence W

doi:10.1203/00006450-198412000-00019

Cited by 3 publications

References 16 publications

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Modification of central venous catheter polymers to prevent in vitro microbial colonisation

Tebbs

Elliott

1994

Eur. J. Clin. Microbiol. Infect. Dis.

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The efficacy of an antimicrobial catheter for the prevention of bacterial colonisation was investigated. The catheter was hydrophilic coated (Hydrocath) and impregnated with the quaternary ammonium antimicrobial agent, benzalkonium chloride (BZC). Microbial colonisation of this central venous catheter was compared to that of polyurethane catheters with or without a hydrophilic coating. Adherence of five strains of Staphylococcus epidermidis to the three catheter types was determined with a microbial colonisation model. Adherence of three strains of Staphylococcus epidermidis to Hydrocath catheters was significantly reduced in comparison to polyurethane catheters (p < 0.01). BZC-impregnated Hydrocath catheters prevented bacterial colonisation of both the internal and external catheter surfaces (p < 0.01). These results were confirmed by scanning electron microscopy. The findings demonstrate that hydrophilic-coated Hydrocath catheters can inhibit bacterial adherence in vitro. Bacterial colonisation was further restricted by the addition of BZC to these coated catheters.

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Modification of central venous catheter polymers to prevent in vitro microbial colonisation

Tebbs

Elliott

1994

Eur. J. Clin. Microbiol. Infect. Dis.

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Carbohydrate supplementary materials

Scanes

2022

Sturkie's Avian Physiology

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Hepatic metabolism of glucose, galactose, and lactate after milk feeding in newborn lambs

Spedale

Battaglia

Sparks

1992

American Journal of Physiology-Endocrinology and Metabolism

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The purpose of this study was to test the ability of the liver to efficiently clear substrates absorbed from the gastrointestinal tract after a feeding before entry into the systemic circulation. We placed a hepatic vein (HV) catheter in utero at 135-140 days gestation. The lamb was then allowed to deliver spontaneously, and additional catheters were placed in the portal vein (PV) and femoral artery (FA) at 1-3 days postnatal age. After at least 2 days recovery, lambs were fasted overnight at 4-10 days of age and then allowed to nurse ad libitum. There was significant hepatic glucose release during fasting and after 80 min postprandially. No net hepatic uptake of glucose was observed before or after feeding. PV galactose was significantly greater than FA and HV from 40 to 160 min after feeding (P less than 0.005). Hepatic glucose extraction was negligible in the fasted state (1 +/- 3%) and increased after feeding to 75 +/- 2% when PV galactose was less than 1.0 mM. There was a significant hepatic arteriovenous concentration difference of lactate (0.23 +/- 0.03 mM) and of oxygen (0.27 +/- 0.01 mM), which did not change significantly after feeding. The metabolic quotient for galactose increased significantly after feeding, such that galactose was the largest carbon contributor for postprandial hepatic carbon accretion. After a milk feeding, the newborn liver efficiently extracts galactose, lactate, and oxygen, but not glucose.

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Splanchnic Uptake and Release of Energy Substrates in the Fasting Baboon Infant

Cited by 3 publications

References 16 publications

Modification of central venous catheter polymers to prevent in vitro microbial colonisation

Modification of central venous catheter polymers to prevent in vitro microbial colonisation

Carbohydrate supplementary materials

Hepatic metabolism of glucose, galactose, and lactate after milk feeding in newborn lambs

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