Spleen angiosarcoma: a world review

Hsien, Brian Lee Juin; Shelat, Vishal G

doi:10.1080/17474124.2021.1945920

Cited by 6 publications

(1 citation statement)

References 129 publications

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“…The accurate diagnosis of splenic angiosarcoma requires a triple assessment, combining clinical examination, imaging findings and pathology ( 21 ). Nonetheless, the heterogeneity of clinical presentations and non-specific imaging findings render the definitive diagnosis of splenic angiosarcoma challenging, with histopathological analysis remaining crucial.…”

Section: Discussionmentioning

confidence: 99%

Metastatic splenic angiosarcoma presenting with anemia and bone marrow fibrosis mimicking primary myelofibrosis: A case report and literature review

Wu,

Li,

Luo

et al. 2024

Mol Clin Oncol

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Angiosarcomas, originating from endothelial cells, are infrequent soft tissue sarcomas characterized by a high propensity for metastasis and an unfavorable prognosis. Splenic angiosarcoma, an exceedingly rare and aggressive neoplasm, exhibits variable clinical manifestations. The present case report describes a patient initially exhibiting anemia and bone marrow fibrosis, mimicking primary myelofibrosis, ultimately diagnosed with splenic angiosarcoma. The findings of the present case report underscore the importance of considering splenectomy for histopathological confirmation. Employing a panel of vascular differentiation markers is invaluable for establishing the diagnosis of angiosarcoma.

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Section: Discussionmentioning

confidence: 99%