Splenic abscess caused by Lactobacillus paracasei

Doi, Asako; Nakajo, Ko; Kamiya, Toru; Ohkusu, Kiyofumi

doi:10.1007/s10156-010-0090-4

Cited by 7 publications

(2 citation statements)

References 19 publications

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“…rhamnosus (among which a case due to consumption of large quantities of fermented milk with the probiotic strain GG in the months before hospitalization; ) were the species most commonly responsible for these pathologies. In recent years, some cases of liver and spleen abscesses caused by lactobacilli have been described . Most of these lactobacillemia cases are associated within the population with a reduced immune function.…”

Section: Safety Assessmentmentioning

confidence: 99%

Microbial characterization of probiotics–Advisory report of the Working Group “8651 Probiotics” of the Belgian Superior Health Council (SHC)

Huys

Botteldoorn

Delvigne

et al. 2013

Molecular Nutrition Food Res

103

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When ingested in sufficient numbers, probiotics are expected to confer one or more proven health benefits on the consumer. Theoretically, the effectiveness of a probiotic food product is the sum of its microbial quality and its functional potential. Whereas the latter may vary much with the body (target) site, delivery mode, human target population, and health benefit envisaged microbial assessment of the probiotic product quality is more straightforward. The range of stakeholders that need to be informed on probiotic quality assessments is extremely broad, including academics, food and biotherapeutic industries, healthcare professionals, competent authorities, consumers, and professional press. In view of the rapidly expanding knowledge on this subject, the Belgian Superior Health Council installed Working Group “8651 Probiotics” to review the state of knowledge regarding the methodologies that make it possible to characterize strains and products with purported probiotic activity. This advisory report covers three main steps in the microbial quality assessment process, i.e. (i) correct species identification and strain-specific typing of bacterial and yeast strains used in probiotic applications, (ii) safety assessment of probiotic strains used for human consumption, and (iii) quality of the final probiotic product in terms of its microbial composition, concentration, stability, authenticity, and labeling.

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Section: Safety Assessmentmentioning

confidence: 99%

Microbial characterization of probiotics–Advisory report of the Working Group “8651 Probiotics” of the Belgian Superior Health Council (SHC)

Huys

Botteldoorn

Delvigne

et al. 2013

Molecular Nutrition Food Res

103

View full text Add to dashboard Cite

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“…They also constitute normal flora of the human vagina, oropharynx, and gastrointestinal tract [4]. However, Lactobacilli can cause infectious diseases, such as bacteremia [5] and endocarditis [6-8], as well as splenic [9,10] and hepatic abscesses [11], in humans. Moreover, Lactobacilli have emerged as pathogenic microbes in both immunocompetent and immunocompromised hosts [12,13].…”

Section: Introductionmentioning

confidence: 99%

Descending necrotizing mediastinitis associated with Lactobacillus plantarum

et al. 2013

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BackgroundDescending necrotizing mediastinitis (DNM), a severe infection with a high fatality rate, develops in mediastinal spaces due mainly to deep cervical abscesses. The majority of causative microbes of DNM are Streptococci and oral anaerobes. DNM associated with Lactobacillus-infection is rather rare.Case presentationA 69-year-old male with an unremarkable past medical history was referred to our hospital for surgical resection of advanced laryngeal cancer. Full examination revealed a neck abscess and DNM with a background of untreated diabetes mellitus. Initially, he was treated with meropenem. However, Lactobacillus plantarum was isolated from surgical drainage of a mediastinal abscess. Despite using antibiotics capable of eradicating all isolates with susceptibilities not differing significantly from those of the neck and mediastinal abscesses, we attributed DNM to the L. plantarum detected only in the mediastinal abscess. After DNM treatment, he underwent total pharyngolaryngectomy with bilateral neck dissection followed by reconstruction using free jejunum. He was discharged fully recovered.ConclusionWe concluded that L. plantarum as the sole cause of the mediastinal abscess in the present case cannot be ruled out. As the number of immunocompromised patients increases, we should be cautious regarding this “familiar” microbe.

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Perinephric Abscess and Bacteremia Due to Lactobacillus Species in a Diabetic Adult

Freitas¹,

Toor²,

Bekele³

et al. 2019

Infect Dis Clin Pract

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Lactobacillus species are a group of anaerobic or facultatively anaerobic, catalase-negative, gram-positive non–spore-forming rods that are usually considered benign commensal organisms present in the human mouth and gastrointestinal and genital tracts. Given their indolent nature, the presence of Lactobacillus species in cultures is often considered contaminants. In rare occasions, however, Lactobacillus species have been reported as pathogens causing a broad range of clinically significant conditions including bacteremia, endocarditis, dental abscesses, meningitis, and intra-abdominal infections such as peritonitis, endometritis, and splenic and liver abscesses. Pyelonephritis has only been seldomly reported in literature, and perinephric abscess has never been reported in literature to date. When infection happens, it usually occurs in immunosuppressed individuals such as those with cancer, transplant recipients, chronic steroid use, or human immunodeficiency virus/AIDS. Despite being gram-positive, the bacteria are usually resistant to vancomycin, and treatment with a penicillin-based regimen is preferred. We describe a case of a diabetic and morbidly obese, but otherwise healthy man, who developed bacteremia and perinephric abscess due to Lactobacillus species.

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Splenic abscess caused by Lactobacillus paracasei

Cited by 7 publications

References 19 publications

Microbial characterization of probiotics–Advisory report of the Working Group “8651 Probiotics” of the Belgian Superior Health Council (SHC)

Microbial characterization of probiotics–Advisory report of the Working Group “8651 Probiotics” of the Belgian Superior Health Council (SHC)

Descending necrotizing mediastinitis associated with Lactobacillus plantarum

Perinephric Abscess and Bacteremia Due to Lactobacillus Species in a Diabetic Adult

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