Splenic infarct presenting as acute chest pain

Abstract

Splenic infarct (SI) is a rare clinical diagnosis typically characterized by symptoms of abdominal pain, nausea, and vomiting. Here we provide a unique case of SI, presenting as acute left-sided chest pain. This unusual presentation led us to incorrectly focus the initial investigation on diseases of cardiac origin. The resultant delay in correct diagnosis of Splenic Infarct and adequate treatment is described. This case highlights the need to consider SI in patients with acute chest pain, particularly in the presence of predisposing factors, such as hematological malignancy or autoimmune rheumatic diseases.

Complete splenic infarction in association with COVID-19

“…The annual incidence rate of splenic infarction is around 1 in 100 000 in the general population. 13 An underlying haematological condition such as sickle cell disease, leukaemia, myelofibrosis or lymphoma, is seen to coexist in 10%-59% of cases reported in the literature. [13][14][15] Other risk factors include cardiovascular disease, hypercoagulability, hypertension, diabetes mellitus and infection.…”

“…13 An underlying haematological condition such as sickle cell disease, leukaemia, myelofibrosis or lymphoma, is seen to coexist in 10%-59% of cases reported in the literature. [13][14][15] Other risk factors include cardiovascular disease, hypercoagulability, hypertension, diabetes mellitus and infection. 15 The most commonly identified signs and symptoms are left upper quadrant pain and tenderness, fevers, and nausea and vomiting.…”