Splenic infarction after histoacryl injection for bleeding gastric varices

Endoscopic hemostasis for bleeding gastric varices treated by combination of variceal ligation and sclerotherapy with N-butyl-2-cyanoacrylate

“…Because of this property, it has been adapted to EIS for actively bleeding gastric varices. 9,19,[32][33][34][35] In this study, we achieved initial hemostasis in 24 of 27 patients (88.9%). Three patients without initial hemostasis did not achieve stable vital signs, and prompt surgical or radiological modalities, including the Hassab procedure and BRTO, could not be applied as suggested in previous reports.…”

Spontaneous splenic infarction in an elderly cirrhotic patient with multiple comorbidities

“…Iatrogenic infarction may occur during selective intraarterial infusion of vasopressin for gastrointestinal bleed, resulting in angiographically demonstrable splenic artery spasm and subsequent splenic infarction in cirrhotic patients (9). There are also case reports of splenic infarction after cyanoacrylate injection to gastric fundal varices (10,11), histoacryl embolization (12)(13)(14), splenic artery ligation (15), and liver transplantation (16). Splenic infarction can be the presenting symptom of other underlying illnesses, so a high index of suspicion for this condition is appropriate in the presence of predisposing conditions for thrombosis, left flank pain, and splenomegaly.…”

Endoscopic Hemoclipping for Bleeding Gastric Varices

“…Endoscopic cyanoacrylate injection for bleeding gastric varices has been widely applied and achieves hemostasis in more than 90% of patients with acute gastric variceal bleeding3). However, severe complications related to embolization in the brain, lung, portal vein, and spleen have raised concerns about the safety of injecting adhesive agents into tissues18, 19). Additionally, the use of cyanoacrylate is only available at Endoclipping of Gastric Varices a limited number of institutes in Japan, and is not officially approved.…”