Splenic Infarction Associated with Acute Brucellosis: A Case Report

Abstract

We report a case of a 21-year-old shepherd who presented with fever, left hypochondrium pain and splenomegaly. Blood tests showed thrombocytopenia and high liver enzymes. Computed tomography scan revealed the presence of hypodense lesions suggestive of splenic infarction. Echocardiography was without abnormalities. Laboratory evaluation for thrombophilia was negative. A bone marrow aspiration and a bone marrow biopsy were normal. Brucella serology was positive. The patient was treated with doxycycline, rifampicin and streptomycin for 12 weeks. Fever, abdominal pain and thrombocytopenia resolved promptly. At one year of follow-up, he remained well and no splenic infarction could be detected on ultrasonography.

A 28-Year-Old Woman with Fever, Weight Loss, Pancytopenia, and Multiple Hepatosplenic and Bone Lesions

“…In Turkey, Pourbagher et al [ 11 ] reviewed 251 cases of brucellosis and identified splenic abscess in 1.6% of cases with an ultrasound. Other rare complications associated with splenic involvement in brucellosis include splenic infarction, [ 12 , 13 ], splenic subcapsular hematoma, and spontaneous splenic rupture [ 5 ]. Most patients with hepatic and splenic abscess due to brucellosis have chronic infection.…”

Deep Venous Thrombosis as a Complication of Brucellosis: A Case Report on Diagnosis and Treatment Management

“…Human brucellosis is common, especially in the Mediterranean region and developing countries [1] . Although osteoarticular involvement is common, vascular complications have rarely been associated with brucellosis [2][3][4][5][6] . Herein, it is aimed to present a case of human brucellosis complicated by deep venous thrombosis.…”

“…Many organ systems may be affected by Brucella infection. Cardiovascular involvement is one of the rare clinical presentations and pericarditis, myocarditis, endocarditis, and vascular involvement have been reported in the literature [2][3][4][5][6][7][8][9] . In our patient, deep venous thrombosis was observed and multiple areas of involvement were detected in the vast majority of the vascular system.…”