2017
DOI: 10.5336/archlung.2017-55426
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Splenic Metastasis in Lung Cancer

Abstract: alak metastazı, nadir görülen ve genellikle yaygın hastalık ile ilişkili bir metastaz şeklidir. Diğer organlar ile karşılaştırıldığında anatomik, fizyolojik ve lenfoid yapısı nedeni ile metastazlara karşı daha dirençlidir. Meme, over, kolorektal sistem, akciğer ve malign melanoma dalak metastazı en sık görülen primer tümörlerdir.1 Tüm organ maligniteleri içinde dalak metastazı görülme sıklığı %2,3 ile 7,1 oranında saptanmaktadır.2 Sıklıkla asemptomatik olmakla birlikte, genel malignite semptomlarına ek olarak;… Show more

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“…When splenic masses and nodules are detected; hemangioma, hamartoma, inflammatory pseudotumor, non-Hodgkin lymphoma and Hodgkin's disease; granulomatous diseases such as sarcoidosis, tuberculosis and histoplasmosis, should be considered in differential diagnosis along with metastasis. It is well known that the spleen is much more protected against metastases due to anatomical, physiological and lymphoid features compared to the organs [9,10]. Splenic capsule, constant blood flow, rhythmic contractility, sharpspins of the spleen artery, high immune cell count and high angiogenesis inhibitory factor levels complicate tumor embolism to reach the spleen [11].…”
Section: Discussionmentioning
confidence: 99%
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“…When splenic masses and nodules are detected; hemangioma, hamartoma, inflammatory pseudotumor, non-Hodgkin lymphoma and Hodgkin's disease; granulomatous diseases such as sarcoidosis, tuberculosis and histoplasmosis, should be considered in differential diagnosis along with metastasis. It is well known that the spleen is much more protected against metastases due to anatomical, physiological and lymphoid features compared to the organs [9,10]. Splenic capsule, constant blood flow, rhythmic contractility, sharpspins of the spleen artery, high immune cell count and high angiogenesis inhibitory factor levels complicate tumor embolism to reach the spleen [11].…”
Section: Discussionmentioning
confidence: 99%
“…Relying on current data, the majority of the primary tumors of splenic metastasis are histologically adenocarcinoma [14]. Primary lung tumor that metastases to spleen is more commonly located on the left lung, as well as in ourcase, depending on the excess of rate of blood flow compared to the right [6,10,15]. Growingnumber of splenic metastases from various solid tumor types have been identified, owing to medical imaging techniques.…”
Section: Discussionmentioning
confidence: 99%
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