2008
DOI: 10.3201/eid1406.071295
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Splenic Rupture and Malignant Mediterranean Spotted Fever

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Cited by 12 publications
(7 citation statements)
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“…In recent times, complicated MSF cases have been reported, even in the absence of predisposing conditions (Colomba et al, 2008;Leone et al, 2008;Tsiachris et al, 2008;Tzavella et al, 2006). The pathogenesis of MSF complications results from vascular injury, which may be responsible for the dysfunction of different organs (Brouqui et al, 2007;Rovery et al, 2008;Schmulewitz et al, 2008). Our patient was previously healthy.…”
Section: Discussionmentioning
confidence: 69%
See 1 more Smart Citation
“…In recent times, complicated MSF cases have been reported, even in the absence of predisposing conditions (Colomba et al, 2008;Leone et al, 2008;Tsiachris et al, 2008;Tzavella et al, 2006). The pathogenesis of MSF complications results from vascular injury, which may be responsible for the dysfunction of different organs (Brouqui et al, 2007;Rovery et al, 2008;Schmulewitz et al, 2008). Our patient was previously healthy.…”
Section: Discussionmentioning
confidence: 69%
“…During the last few years rickettsial diseases have emerged in several Mediterranean countries (Rovery et al, 2008;Schmulewitz et al, 2008;Boillat et al, 2008;Weinberger et al, 2008). Until the 1980s, MSF was thought to be a benign illness with few complications and the proportion of deaths was ,1 %.…”
Section: Discussionmentioning
confidence: 99%
“…22 A ruptured spleen is a rare complication in patients with scrub typhus, 23 murine typhus, 24 and Mediterranean spotted fever group. 25 Nevertheless, splenic rupture is a known complication of various infectious diseases such as Epstein-Barr virus (infectious mononucleosis), 26 and malaria. 27 Spontaneous splenic rupture is a life-threatening condition if not recognized and appropriately managed.…”
Section: Discussionmentioning
confidence: 99%
“…It was estimated that about 5–10% of MSF cases could be severe. Cases of severe respiratory distress syndrome, 57 cardiovascular symptoms (coronary ectasia, 58 myocarditis, 59 , 60 vasculitis 61 ) ocular symptoms, 62 65 neurological symptoms 66 , 67 (sensorineural hearing lost, 68 , 69 polyneuropathy, 70 , 71 encephalitis, 72 , 73 meningitis 74 , 75 ), acute pancreatitis, 76 splenic rupture, 77 acute renal failure, 73 hemophagocytic syndrome 78 – 80 and arthritis 81 , 82 have been reported.…”
Section: Clinical Manifestationmentioning
confidence: 99%