2010
DOI: 10.1177/000313481007600508
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Splenic Rupture Secondary to Venous Thrombosis in a Patient with Ulcerative Colitis and Toxic Megacolon

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“…Aside from pancreatitis, there have been reported cases of splenic vein thromboses due to cardiac surgery, septic emboli from infective endocarditis, and atherosclerosis from chronic renal failure [8] , [9] , [10] , [11] . There also has been a reported incidence of toxic megacolon from underlying ulcerative colitis, which can cause splenic venous thrombosis and lead to splenic rupture [12] . Thrombophilia in patients afflicted with paroxysmal nocturnal hemoglobinuria has been documented to have caused splenic rupture through splenic venous thrombosis [13] .…”
Section: Discussionmentioning
confidence: 99%
“…Aside from pancreatitis, there have been reported cases of splenic vein thromboses due to cardiac surgery, septic emboli from infective endocarditis, and atherosclerosis from chronic renal failure [8] , [9] , [10] , [11] . There also has been a reported incidence of toxic megacolon from underlying ulcerative colitis, which can cause splenic venous thrombosis and lead to splenic rupture [12] . Thrombophilia in patients afflicted with paroxysmal nocturnal hemoglobinuria has been documented to have caused splenic rupture through splenic venous thrombosis [13] .…”
Section: Discussionmentioning
confidence: 99%