Splenic Venography Demonstration of the Portal Circulation With Diodone

Dreyer, B.; Budtz-Olsen, O.E.

doi:10.1016/s0140-6736(52)90394-2

Cited by 38 publications

(6 citation statements)

References 5 publications

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“…Twenty-six cases had splenovenograms and in 37 the intrasplenic pressure was estimated by the percutaneous route (Dreyer and Budtz-Olsen, 1952;Atkinson and Sherlock, 1954). Splenic puncture specimens were examined for malaria parasites and leishmaniae.…”

Section: Methodsmentioning

confidence: 99%

An Investigation of Tropical Splenomegaly at Mulago Hospital, Kampala, Uganda

Marsden¹,

Hutt²,

Wilks³

et al. 1965

BMJ

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Idiopathic, cryptogenic, or tropical splenomegaly, as it is variously termed, is often encountered at the Mulago Hospital in Kampala. Trowell (1950) reported several cases in which no good reason could be found for gross splenomegaly, and discussed the current theories of aetiology. Leather (1961) made the important observation that many cases had a mild portal hypertension in the absence of any evidence of cirrhosis on liver biopsy. Of the 41 cases he investigated 29 showed sinusoidal infiltrates by lymphocytes, histiocytes, and plasma cells, an appearance that had been noted elsewhere in the tropics by Fawdry (1955) from Aden, and by Chaudhuri et al. (1956) from India.The present report describes a series of cases of marked splenomegaly admitted to the New Mulago Hospital, Kampala, in which combined clinical, haematological, parasitological, and pathological investigations were carried out to assess the cause and effect of the large spleens. Materials and MethodsOver a period of eight months 64 patients with marked splenomegaly were investigated in the New Mulago Hospital, Kampala.Routine haematological investigations were prepared by standard techniques (Dacie, 1956). In five patients the red-cell survival and splenic uptake were estimated, using 5Cr-tagged red cells (Mollison and Veall, 1955), and the sites of red-cell destruction were assessed by the method of Hughes Jones and Szur (1957 BudtzOlsen, 1952;Atkinson and Sherlock, 1954). Splenic puncture specimens were examined for malaria parasites and leishmaniae. Initially, random peripheral thick blood was examined for malaria parasites and trypanosomes, but in the latter part of the study a minimum of 10 consecutive daily blood films were examined for malaria parasites by two observers.Stools were examined by the formol-ether-concentration technique (Ridley and Hawgood, 1956) for ova, cysts, and parasites. Rectal snips were examined for schistosome ova.Sera from 40 patients were examined by a fluorescent antibody technique (Voller, 1964) for the presence of malarial antibodies. Control sera from patients without splenomegaly were also examined. The antigen used was Plasmodium bastianellii.

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Section: Methodsmentioning

confidence: 99%

An Investigation of Tropical Splenomegaly at Mulago Hospital, Kampala, Uganda

Marsden¹,

Hutt²,

Wilks³

et al. 1965

BMJ

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“…Venous segmentation in the human spleen have been reported by Dreyer and Budtz-Olsen [1952] and Fuld and Irwin [1954] during diagnostic splenic venogra phy. Gupta et al [1980] found 2-4 venous segments in 92.7% (102 cases) of human spleens in the corrosion casts of the splenic veins and its intrasplenic tree, with a number of variations in their pattern.…”

Section: Discussionmentioning

confidence: 95%

Study of Venous Segments in the Spleens of Buffalo and Dog

Gupta¹,

Gupta²,

Gupta³

1981

Cells Tissues Organs

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By preparing the corrosion cast of the splenic vein and its intrasplenic tree, venous segments have been observed in the spleens of buffalo and dog. The buffalo spleen showed the presence of two venous segments (a dorsal and a ventral) in 85% of cases and three (a dorsal, an intermediate and a ventral) in 15% of cases. The spleen of the dog revealed only two venous segments (a dorsal and a ventral) in all the specimens. The results are compared with descriptions available in the literature.

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“…The diagnosis can be confirmed and the exact site of obstruction demonstrated pre-operatively. In addition, as has been suggested before [Dreyer and Budtz-Olsen, 1952], and as Jahnke, Palmer, Sborov, Hughes and Seeley [1953] have shown, the patency of a porta-caval anastomosis can be determined if the spleen has not been removed previously. It appears to be a safe method applicable to humans with enlarged spleens.…”

Section: Dreyermentioning

confidence: 89%

“…An X-ray photograph of the upper abdomen was taken at the end of injection. The details of the technique have been described elsewhere [Dreyer and Budtz-Olsen, 1952].…”

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confidence: 99%

Splenic and Portal Venography

Dreyer

1954

Exp Physiol

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1. The splenic and portal veins can be demonstrated by the injection of radio‐opaque dye into the spleen. This has been done in dogs with exteriorised or subcutaneous spleens, and in humans with enlarged spleens by direct injection. 2. The injected dye leaves the spleen quickly and in large amounts, and demonstrates the sizes of the splenic and portal veins. 3. In the absence of portal obstruction a filling defect is present where the superior mesenteric flow meets the splenic. 4. In the presence of portal obstruction the site of obstruction is indicated. In addition, collateral veins are filled with dye, the portal vein is dilated and a reflux of dye may occur into the superior mesenteric vein. Changes in the direction of blood flow in the portal tributaries may be shown. 5. The intrahepatic portal branches appear to be fewer, coarser and further apart in cirrhosis of the liver.

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Splenic Venography Demonstration of the Portal Circulation With Diodone

Cited by 38 publications

References 5 publications

An Investigation of Tropical Splenomegaly at Mulago Hospital, Kampala, Uganda

An Investigation of Tropical Splenomegaly at Mulago Hospital, Kampala, Uganda

Study of Venous Segments in the Spleens of Buffalo and Dog

Splenic and Portal Venography

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