Splinter Hemorrhage

Nitrofurantoin-induced splinter hemorrhages: A forgotten culprit

“…The discovery of splinter hemorrhages dates back to the 1920s, when Blumer described subungual bleeding that looked identical to splinters under the nails. 4 Excluding its common idiopathic nature, trauma and bacterial endocarditis as the most common etiology of this condition, multiple drugs and dermatologic conditions have been associated with splinter hemorrhages as well. This includes but is not limited to septic embolization, central venous and foley catheter infections, graft infections or failures, sepsis, meningococcemia, systemic lupus erythematosus, or vasculitis.…”