Split‐thickness skin grafting in postmastoidectomy revision and in lateral temporal bone resection

Renton, John P.; Wetmore, Stephen J.

doi:10.1016/j.otohns.2005.10.065

Cited by 8 publications

(3 citation statements)

References 17 publications

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“…A study conducted by Renton and Wetmore 13 was similar to our study. In the study by Renton and Wetmore, split-thickness grafting was performed on post-mastoidectomy revision and lateral temporal bone resection cases.…”

Section: Discussionsupporting

confidence: 90%

“…Initially, the graft survived through serum imbibition and graft revascularisation took place later on. 13 • Cavity healing after a canal wall down mastoidectomy is a challenge • Incomplete epithelialisation is one of the causes of delayed healing • Temporalis fascia superimposed with free skin grafts were used in this study • This technique promoted healing mainly in the first three months after surgery • This technique did not affect residual or recurrent disease or the flora of the post-operative discharge • This technique can be easily adopted after every canal wall down mastoidectomy procedure…”

Section: Discussionmentioning

confidence: 98%

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The effect of fascia and free skin graft on the healing of mastoid cavity after canal wall down mastoidectomy

2021

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Objective Post-mastoidectomy delayed cavity healing is a challenge to manage. This study aimed to cut down healing time with a simple technique (fascia with a skin graft) and compared it with controls without this technique. Method The current study was a prospective non-randomised controlled study, conducted in a tertiary referral hospital. Thirty cases and 30 controls with squamosal type chronic otitis media were studied. Results By the end of first month, 23.3 per cent of cases had healed compared with 3.3 per cent of controls. At the third month follow up, 83.3 per cent of cases and 53.3 per cent of controls had healed. At the sixth month follow up, 93.3 per cent of cases and 86 per cent of controls had healed. Conclusion Healing of the mastoid cavity, as evidenced by epithelialisation and formation of a dry cavity, was faster in cases that received the graft when compared with controls without the graft.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 98%

The effect of fascia and free skin graft on the healing of mastoid cavity after canal wall down mastoidectomy

2021

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“…Efforts have been made to halt otorrhea and infection by obliterating the mastoid cavity with a thick skin graft, [2] a temporal muscle fascia-periosteum flap, [3] bone pate, [4] and beta-tricalcium phosphate [5] . However, none of these techniques have achieved satisfactory results.…”

Section: Introductionmentioning

confidence: 99%

Epithelial defect repair in the auricle and auditory meatus by grafting with cultured adipose-derived mesenchymal stem cell aggregate-extracellular matrix

Zhang

Ming

Sun

2019

Chinese Medical Journal

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Background:Several patients experience persistent otorrhea after a flawless surgical procedure because of insufficient epithelial healing. Several efforts, such as autologous tissue allograft and xenograft, have been made to halt otorrhea. However, a stable technology to induce temporal epithelial repair is yet to be established. Therefore, this study aims to investigate whether implantation of seeding adipose-derived mesenchymal stem cell (ADMSC) aggregates on extracellular matrix (ECM; herein, ADMSC aggregate-ECM) into damaged skin wound promotes skin regeneration.Methods:ADMSC aggregate-ECM was prepared using a previously described procedure that isolated ADMSCs from rabbits and applied to the auricle and auditory meatus wound beds of New Zealand white rabbits. Wound healing was assessed by general observation and hematoxylin and eosin (H&E) staining. Secretion of growth factor of the tissue was evaluated by western blotting. Two other groups, namely, ECM and control, were used. Comparisons of three groups were conducted by one-way analysis of variance analysis.Results:ADMSCs adhered tightly to the ECM and quickly formed cell sheets. At 2 weeks, general observation and H&E staining indicated that the wound healing rates in the ADMSC aggregate-ECM (69.02 ± 6.36%) and ECM (59.32 ± 4.10%) groups were higher than that in the control group (43.74 ± 12.15%; P = 0.005, P < 0.001, respectively) in ear auricle excisional wounds. At 7 weeks, The scar elevation index was evidently reduced in the ADMSC aggregate-ECM (2.08 ± 0.87) and ECM (2.31 ± 0.33) groups compared with the control group (4.06 ± 0.45; P < 0.001, P < 0.001, respectively). In addition, the scar elevation index of the ADMSC aggregate-ECM group reached the lowest rate 4 weeks in advance. In auditory meatus excisional wounds, the ADMSC aggregate-ECM group had the largest range of normal skin-like structure at 4 weeks. The ADMSC aggregate–ECM and ECM groups secreted increased amounts of growth factors that contributed to skin regeneration at weeks 1 and 2, respectively.Conclusions:ADMSC aggregate-ECM and ECM are effective repair materials for wound healing, especially ADMSC aggregate-ECM. This approach will provide a meaningful experimental basis for mastoid epithelium repair in subsequent clinical trials.

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Lateral Temporal Bone Resection

Gidley

2018

Temporal Bone Cancer

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Split‐thickness skin grafting in postmastoidectomy revision and in lateral temporal bone resection

Abstract: Placement of STSG is a useful adjunct in revision CWD mastoidectomy as well as in primary LTBR for cancer.

Cited by 8 publications

References 17 publications

The effect of fascia and free skin graft on the healing of mastoid cavity after canal wall down mastoidectomy

The effect of fascia and free skin graft on the healing of mastoid cavity after canal wall down mastoidectomy

Epithelial defect repair in the auricle and auditory meatus by grafting with cultured adipose-derived mesenchymal stem cell aggregate-extracellular matrix

Lateral Temporal Bone Resection

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