Spondylodiscitis due to anaerobic bacteria Veillonella parvula: Case report and literature review

Abstract

Background: While pyogenic spondylodiscitis due to Gram-positive aerobic bacteria and its treatment is well known, spondylodiscitis caused by anaerobic Gram-negative pathogen is rare. In particular, the spondylodiscitis caused by Veillonella species is an absolute rarity. Thus no established management recommendations exist. Case Description: A case report of a 79-year-old man with spondylodiscitis caused by Veillonella parvula with intramuscular abscess collection managed conservatively with stand-alone antibiotic therapy without a spinal stabilization procedure. A review of literature of all reported spondylodiscitis caused by Veillonella species was performed. After 3 week-intravenous therapy with the ceftriaxone in combination with the metronidazole followed by 3 weeks per oral therapy with amoxicillin/clavulanate, the complete recovery of the patient with the V. parvula infection was achieved. Conclusion: Treatment of the spondylodiscitis caused by Veillonella species should contain a beta-lactam with beta-lactamase inhibitor or third-generation cephalosporine. Six weeks of treatment seem to be sufficient for the complete recovery of the patient.

Multi-modal molecular determinants of clinically relevant osteoporosis subtypes

“…4b ). There are many case reports regarding the contribution of Veillonella parvula to various bone diseases, including spondylodiscitis, osteomyelitis and primary sclerosing cholangitis 34 – 36 . Recent studies have further suggested an association between osteoporosis and these bone dysfunctions.…”