Spondylosis and Osteoporotic Vertebral Fractures

Miyakoshi, Naohisa; Kodama, Hiroyuki; Kasukawa, Yuji; Kobayashi, Takashi; Suzuki, Tetsuya; Abe, Tomoki; Abe, Eiji; Shimada, Yasuhiro

doi:10.1007/978-4-431-55778-4_7

Cited by 2 publications

(2 citation statements)

References 55 publications

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“…4 Lumbar interbody fusions are one such treatment option for degenerative disc disease and spondylolisthesis. 5 Early techniques often required significant tissue dissection and muscle disruption in order to expose traditional gross anatomical landmarks for the purpose of interbody placement and pedicle screw insertion. The rapid popularization of minimally invasive spine (MIS) surgery has obviated this need, and as a result, modern methods now rely moreso on navigation and fluoroscopy and can accomplish anatomically similar surgeries through smaller incisions.…”

Section: Introductionmentioning

confidence: 99%

Percutaneous Lumbar Interbody Fusion With an Expandable Titanium Cage Through Kambin’s Triangle: A Case Series With Initial Clinical and Radiographic Results

et al. 2021

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Background: There has been an increased interest in lumbar interbody fusions through Kambin's triangle. In this study, we describe percutaneous access to the lumbar disc and insertion of an expandable titanium cage through Kambin's triangle without facetectomy. The objective of this study is to determine the feasibility as well as clinical and radiographical outcomes of completely percutaneous lumbar interbody fusion (percLIF) using an expandable titanium cage through Kambin's triangle.Methods: A retrospective review of patients undergoing single-level percLIF for grade 1 lumbar spondylolisthesis via Kambin's triangle using an expandable titanium cage was performed. Demographic information, Oswestry Disability Index (ODI), preoperative and postoperative radiographic factors, perioperative data, and complications were recorded. Fusion was assessed with 1-year postoperative computed tomography scan or lumbar spine x-ray and defined as bridging disc or posterolateral fusion without evidence of hardware fracture or perihardware lucency.Results: A total of 16 patients (3 males) were included in this study. Spondylolisthesis, anterior disc height, and posterior disc height were significantly improved at 6 weeks, 6 months, and 12 months, postoperatively (P < 0.05). ODI was significantly improved by 24.4% at 12 months postoperatively (P = 0.0036). One patient was readmitted within 30 days for pain control but otherwise there were no complications including permanent neurological injury, infection, deep vein thrombosis, pulmonary embolism, or cardiac events. Fifteen (93.8%) patients had radiographic fusion at their 1-year postoperative imaging.Conclusion: Our initial experiences have shown that percLIF can be performed using an expandable titanium cage through Kambin's triangle with excellent radiographic and clinical results. In this series, percLIF is a safe and clinically efficacious procedure for reducing grade 1 lumbar spondylolisthesis and improving radiculopathy. This procedure is completed percutaneously without the use of an endoscope.Clinical Relevance: This study highlights improvements in outcomes of minimally invasive surgery.

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Section: Introductionmentioning

confidence: 99%

Percutaneous Lumbar Interbody Fusion With an Expandable Titanium Cage Through Kambin’s Triangle: A Case Series With Initial Clinical and Radiographic Results

et al. 2021

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“…In addition, BMD obtained by dual-energy X-ray absorptiometry (DXA) can be used to diagnose osteoporosis, assess the risk of developing fragility fractures (Medical Advisory, 2006;Chen et al, 2022), track changes in the severity of osteoporosis, and assess the effects of certain habit changes or efficacy of medications (Lopez-Peralta et al, 2022). Osteoporosis is mainly divided into primary and secondary osteoporosis (Miyakoshi et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Higher serum apolipoprotein B level will reduce the bone mineral density and increase the risk of osteopenia or osteoporosis in adults

Zhu

Zhao-fu³

et al. 2022

Front. Cell Dev. Biol.

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Objective: There is very limited evidence in the NHANES database linking serum apolipoprotein B and lumbar bone mineral density (BMD) in adults aged 20–59 years. There are few studies associating apolipoprotein B concentrations with BMD, and there is some debate about the association between obesity and BMD. Therefore, the purpose of this study was to determine the association between serum apolipoprotein B concentrations and lumbar spine BMD in adults aged 20–59 years and to predict its association with risk of osteopenia or osteoporosis.Methods: A cross-sectional study of the entire US ambulatory population was conducted using data from the National Health and Nutrition Examination Survey (NHANES) database. Weighted multiple regression equation models were used to assess the association between serum apolipoprotein B and lumbar BMD. A logistic weighted regression model was used to assess the association between serum apolipoprotein B concentrations and risk of osteopenia or osteoporosis. Subsequent stratified analyses were performed to refine the primary population of association.Results: Our study showed a significant negative association between serum apolipoprotein B concentration and lumbar BMD and a significant positive association with the risk of osteoporosis or osteopenia in the total population. After stratifying by sex, age and race, we concluded differently. The association of serum apolipoprotein B concentration with lumbar spine BMD and risk of osteopenia or osteoporosis was significant in male, but not in female. After stratification by age, the negative association between serum apolipoprotein B concentrations and lumbar BMD and the positive association with risk of osteopenia or osteoporosis was more significant in the 30–39 and 50–59 years age groups. When stratified by race, serum apolipoprotein B concentrations were significantly negatively associated with lumbar BMD and positively associated with risk of osteopenia or osteoporosis in Mexican American and non-Hispanic black populations. Thus, these findings suggest that these associations are influenced by sex, age, and race, respectively.Conclusion: Our results suggest that the association between serum apolipoprotein B levels and the risk of lumbar BMD and osteopenia or osteoporosis varies by sex, age, and race. In men, elevated serum apolipoprotein B levels were negative for bone quality. Elevated serum apolipoprotein B levels in the age groups 30–39 and 50–59 years also had a negative effect on bone quality. In the Mexican American and Non-Hispanic Black populations, elevated serum apolipoprotein B levels also had a significant negative effect on bone quality.

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Spondylosis and Osteoporotic Vertebral Fractures

Cited by 2 publications

References 55 publications

Percutaneous Lumbar Interbody Fusion With an Expandable Titanium Cage Through Kambin’s Triangle: A Case Series With Initial Clinical and Radiographic Results

Percutaneous Lumbar Interbody Fusion With an Expandable Titanium Cage Through Kambin’s Triangle: A Case Series With Initial Clinical and Radiographic Results

Higher serum apolipoprotein B level will reduce the bone mineral density and increase the risk of osteopenia or osteoporosis in adults

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