Sponsorship, authorship, and accountability

Políticas de conflito de interesses e exigências para divulgação em Revistas Científicas de Cardiologia Nacionais da Sociedade Europeia de Cardiologia

“…More than 75% of all clinical trials are funded by drug companies 25,26 . Likewise, the bulk of research has moved from academic centres to direct contracts between sponsors and private organisations 27,28 . For-profit, contract research organisations, currently consume more than 60% of research funding from industry [25][26][27][28] .…”

“…Likewise, the bulk of research has moved from academic centres to direct contracts between sponsors and private organisations 27,28 . For-profit, contract research organisations, currently consume more than 60% of research funding from industry [25][26][27][28] . This could be a result of their ability to complete trials more rapidly than academic institutions 8,25 .…”

“…This could be a result of their ability to complete trials more rapidly than academic institutions 8,25 . This phenomenon explains the gradual loss of the academic establishment's influence on the 'research agenda' [25][26][27][28][29] . Although the most cited articles continue to be generated by authors with academic affiliations, the number of trials financed exclusively by industry has increased exponentially 30 .…”

“…This paradigm shift has major consequences [25][26][27][28][29] . First, many scientifically relevant issues are decreasingly likely to be investigated (orphan studies).…”

Cancer clinical trial recruitment

“…3 4 Together, these reports raise con-cerns about the conduct of clinical research, about the competing status of clinician/entrepreneur and treating physician, and about the management of institutional conflicts of interest in the case of research involving human participants. Patients participate in clinical trials for a variety of reasons.…”