Spontan rupturiertes Angiomyolipom der Nebenniere

Stolle, H; Jonetz-Mentzel, L.; Aw, Krautschick-Wilkens

doi:10.1055/s-2006-944287

Cited by 3 publications

(3 citation statements)

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“…A review of the literature revealed 17 previously reported cases of adrenal angiomyolipoma. Of these, 14 were sporadic and 3 were reported in patients with tuberous sclerosis or lymphangioleiomyomatosis [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. There was 1 reported case of spontaneous haemorrhage [4].…”

Section: Discussionmentioning

confidence: 99%

“…They are benign endocrinologically inactive tumours with a histological structure consisting of variable amounts of adipose, thick-walled blood vessels and smooth muscle cells [1]. Commonly, angiomyolipomas occur in the kidney with few extra renal case reports in adrenals, bone, breast, colon, heart, liver, lung, parotid gland, retroperitoneum, skin and spermatic cord [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

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Spontaneous haemorrhage of an adrenal angiomyolipoma: case report

et al. 2019

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Background: Angiomyolipomas are rare mesenchymal tumours arising from the perivascular epithelioid cells consisting of variable amounts of adipose, thick-walled blood vessels and smooth muscle cells. These benign tumours commonly occur in the kidney with only a few case reports of adrenal angiomyolipomas which have the potential to reach a large size and haemorrhage. Case presentation: A 45-year-old lady presented with a 3-week history of right loin pain, nausea and vomiting. A CT scan revealed a right adrenal angiomyolipoma measuring 6.3 × 6.8 cm with associated haemorrhage. The lesion was successfully treated with right open adrenalectomy, and histology confirmed the diagnosis of adrenal angiomyolipoma. The patient remained well with no evidence of recurrence at the 36-month follow-up. Conclusion: Adrenal angiomyolipomas are rare benign tumours that have the ability to reach a large size and potential to bleed. Here, we report the second case of spontaneous haemorrhage in an adrenal angiomyolipoma, which was successfully treated with open adrenalectomy.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Spontaneous haemorrhage of an adrenal angiomyolipoma: case report

et al. 2019

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“…Surgical management has been proposed for lesions >5cm, even if non-functional, to avoid complications of free spontaneous rupture as some such cases in patients on anticoagulants have been reported, for example by Stolle et al 15 The surgical technique for removal of angiomyolipomas can be open or laparoscopic. With recent advances in the laparoscopic technique, even large angiomyolipomas have been removed with a flank-based transperitoneal laparoscopic approach, 16 – 17 indicating a gradual progression towards being less dependent on tumour size before deciding on one particular technique.…”

Section: Managementmentioning

confidence: 99%

Pathophysiology and management aspects of adrenal angiomyolipomas

Hussain

Al-Hamali

2012

annals

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Angiomyolipomas are benign mesenchymal tumours originating from the kidney and adrenals. They are rare tumours that can be sporadic and isolated or occur as a part of tuberous sclerosis. These tumours have a high content in the cells, which is pathognomonic for diagnosis using ultrasonography, computed tomography and magnetic resonance imaging. Atypical angiomyolipomas occur with excessive smooth muscle cells and less adipose tissue, and are sensitive to immunohistochemistry studies. Most of these lesions are detected incidentally but some can cause back and abdominal pains if large in size. Larger lesions are also vulnerable to spontaneous or traumatic rupture, causing large retropertitoneal bleeds. Surgery should be considered as the definitive management for larger lesions to avoid associated complications. There have been no reports of any malignant change being reported in any of the lesions but a long follow-up period is still required, given the unknown clinical progression of these rare tumours.

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